Significance of follow-up thoracic imaging in myasthenia gravis

Hiroyuki Murai, Yuriko Nagane, Shigeaki Suzuki, Tomihiro Imai, Masakatsu Motomura, Kimiaki Utsugisawa

Research output: Contribution to journalArticle

Abstract

Objectives: Most patients with myasthenia gravis (MG) undergo thoracic imaging at initial diagnosis. However, the follow-up protocol is unclear. The objective of the present study was to clarify the follow-up status and main findings of thoracic imaging in patients with MG. Methods: A total of 649 patients with disease duration ≥1 year were included in the study. The follow-up rate and time from the initial scan to the latest thoracic imaging were evaluated. The rate of abnormality and details of abnormal findings in both non-thymomatous MG and thymoma-associated MG were investigated. Results: The follow-up thoracic imaging rate of 145 patients with thymoma-associated MG was 71.7%, whereas just 46.2% of 504 patients with non-thymomatous MG underwent follow-up imaging. Abnormal findings were detected in 8.6% of patients with non-thymomatous MG and 26.0% of those with thymoma-associated MG. Abnormal findings included cancer, lung infection and lymph node swelling in the former, and relapse or increased size of thymoma in the latter. Conclusions: Frequent follow up by thoracic imaging is necessary in patients with MG.

Original languageEnglish
Pages (from-to)246-250
Number of pages5
JournalClinical and Experimental Neuroimmunology
Volume9
Issue number4
DOIs
Publication statusPublished - 2018 Nov 1

Keywords

  • cancer
  • myasthenia gravis
  • thoracic imaging
  • thymoma

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Immunology
  • Immunology and Microbiology (miscellaneous)
  • Clinical Neurology

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