Simple syntheses of 3,4-dideoxy-oct-2-ulosonic acids

Tony K.M. Shing

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

Bisacetonated aldehydo-d-arabinose has been converted by three consecutive reactions (Wittig reaction, catalytic hydrogenation, and hydrolysis) into 3,4-dideoxy-d-arabino-oct-2-ulosonic acid (4-deoxy-KDO), isolated as its calcium salt in an overall yield of 37% from d-arabinose. Likewise reactions of d-xylose gave calcium 3,4-dideoxy-d-xylo-oct-2-ulosonate in an overall yield of 34%.

Original languageEnglish
Pages (from-to)1307-1308
Number of pages2
JournalTetrahedron Letters
Volume33
Issue number10
DOIs
Publication statusPublished - 1992 Mar 3

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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