Abstract
Purpose To evaluate the effectiveness of the single-energy metal artifact reduction (SEMAR) technique for improving the accuracy of I-125 seed identification in postimplant computed tomography (CT) after prostate brachytherapy. Methods and Materials Postimplant CT images of 40 patients treated with I-125 prostate brachytherapy were acquired. For all patients, 2 data sets were reconstructed, 1 with SEMAR algorithms (SEMAR image), and the other without SEMAR algorithms (non-SEMAR image). Seed locations are automatically detected by the automatic seed finder tool, and their locations were compared between the SEMAR and non-SEMAR images. Dosimetric parameters using seed locations as detected were compared. Results The true-positive fraction of properly detected seeds on the SEMAR image as determined from a reference seed distribution defined by one investigator was significantly higher than the true-positive fraction on the non-SEMAR image (p = 0.011). The variabilities in D90 (p = 0.001), V100 (p = 0.007), and V150 (p = 0.007) were significantly reduced for seed location on the SEMAR image as compared with non-SEMAR image. Conclusions Prostate postimplant CT with SEMAR improved the accuracy of seed localization and postimplant dosimetric parameters.
| Original language | English |
|---|---|
| Pages (from-to) | 768-773 |
| Number of pages | 6 |
| Journal | Brachytherapy |
| Volume | 15 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2016 Nov 1 |
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Keywords
- Brachytherapy
- I-125
- Metal artifact reduction
- Prostate
ASJC Scopus subject areas
- Oncology
- Radiology Nuclear Medicine and imaging
Cite this
Single-energy metal artifact reduction in postimplant computed tomography for I-125 prostate brachytherapy : Impact on seed identification. / Shiraishi, Yutaka; Yamada, Yoshitake; Tanaka, Tomoaki; Eriguchi, Takahisa; Nishimura, Shuichi; Yoshida, Kayo; Hanada, Takashi; Ohashi, Toshio; Shigematsu, Naoyuki; Jinzaki, Masahiro.
In: Brachytherapy, Vol. 15, No. 6, 01.11.2016, p. 768-773.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Single-energy metal artifact reduction in postimplant computed tomography for I-125 prostate brachytherapy
T2 - Impact on seed identification
AU - Shiraishi, Yutaka
AU - Yamada, Yoshitake
AU - Tanaka, Tomoaki
AU - Eriguchi, Takahisa
AU - Nishimura, Shuichi
AU - Yoshida, Kayo
AU - Hanada, Takashi
AU - Ohashi, Toshio
AU - Shigematsu, Naoyuki
AU - Jinzaki, Masahiro
PY - 2016/11/1
Y1 - 2016/11/1
N2 - Purpose To evaluate the effectiveness of the single-energy metal artifact reduction (SEMAR) technique for improving the accuracy of I-125 seed identification in postimplant computed tomography (CT) after prostate brachytherapy. Methods and Materials Postimplant CT images of 40 patients treated with I-125 prostate brachytherapy were acquired. For all patients, 2 data sets were reconstructed, 1 with SEMAR algorithms (SEMAR image), and the other without SEMAR algorithms (non-SEMAR image). Seed locations are automatically detected by the automatic seed finder tool, and their locations were compared between the SEMAR and non-SEMAR images. Dosimetric parameters using seed locations as detected were compared. Results The true-positive fraction of properly detected seeds on the SEMAR image as determined from a reference seed distribution defined by one investigator was significantly higher than the true-positive fraction on the non-SEMAR image (p = 0.011). The variabilities in D90 (p = 0.001), V100 (p = 0.007), and V150 (p = 0.007) were significantly reduced for seed location on the SEMAR image as compared with non-SEMAR image. Conclusions Prostate postimplant CT with SEMAR improved the accuracy of seed localization and postimplant dosimetric parameters.
AB - Purpose To evaluate the effectiveness of the single-energy metal artifact reduction (SEMAR) technique for improving the accuracy of I-125 seed identification in postimplant computed tomography (CT) after prostate brachytherapy. Methods and Materials Postimplant CT images of 40 patients treated with I-125 prostate brachytherapy were acquired. For all patients, 2 data sets were reconstructed, 1 with SEMAR algorithms (SEMAR image), and the other without SEMAR algorithms (non-SEMAR image). Seed locations are automatically detected by the automatic seed finder tool, and their locations were compared between the SEMAR and non-SEMAR images. Dosimetric parameters using seed locations as detected were compared. Results The true-positive fraction of properly detected seeds on the SEMAR image as determined from a reference seed distribution defined by one investigator was significantly higher than the true-positive fraction on the non-SEMAR image (p = 0.011). The variabilities in D90 (p = 0.001), V100 (p = 0.007), and V150 (p = 0.007) were significantly reduced for seed location on the SEMAR image as compared with non-SEMAR image. Conclusions Prostate postimplant CT with SEMAR improved the accuracy of seed localization and postimplant dosimetric parameters.
KW - Brachytherapy
KW - I-125
KW - Metal artifact reduction
KW - Prostate
UR - http://www.scopus.com/inward/record.url?scp=84997706146&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84997706146&partnerID=8YFLogxK
U2 - 10.1016/j.brachy.2016.07.006
DO - 10.1016/j.brachy.2016.07.006
M3 - Article
C2 - 27592130
AN - SCOPUS:84997706146
VL - 15
SP - 768
EP - 773
JO - Brachytherapy
JF - Brachytherapy
SN - 1538-4721
IS - 6
ER -