Small deformation of a nearly circular lipid-raft in the stagnation flow

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A lipid-raft-a non-caveolar microdomain enriched with sphingolipids and cholesterol-is thought to be unable to grow beyond a certain size in the biomembrane in vivo. The membrane can accommodate two-dimensional flow, which could break up a larger raft. As a fundamental problem of this mechanism, a small raft-deformation in the stagnation flow is studied in this paper. The capillary number-a relevant dimensionless factor in this problem-involves viscosity of the surrounding fluids for a large enough raft, and instead that of the membrane for a small enough raft. Discussing the breakup condition of a raft, we also show that an estimate of the critical raft-size is consistent with previous observations in vivo.

Original languageEnglish
Pages (from-to)642-647
Number of pages6
JournalJournal of the Physical Society of Japan
Volume74
Issue number2
DOIs
Publication statusPublished - 2005 Feb

Fingerprint

stagnation flow
rafts
lipids
membranes
two dimensional flow
cholesterol
viscosity
fluids
estimates

Keywords

  • Cytoplasmic streaming
  • Lipid-bilayer membrane
  • Phase separation
  • Stokes equation

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Small deformation of a nearly circular lipid-raft in the stagnation flow. / Fujitani, Youhei.

In: Journal of the Physical Society of Japan, Vol. 74, No. 2, 02.2005, p. 642-647.

Research output: Contribution to journalArticle

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