Small RNAs: Artificial piRNAs for transcriptional silencing

Takamasa Hirano, Haruhiko Siomi

Research output: Contribution to journalShort survey

1 Citation (Scopus)

Abstract

Technologies have been developed in animal germ cells that produce artificial piRNAs from transgenes in piRNA clusters to silence target genes by cleaving their transcripts. A new study provides a simple way to generate artificial piRNAs to direct de novo DNA methylation in mice.

Original languageEnglish
Pages (from-to)R280-R283
JournalCurrent Biology
Volume25
Issue number7
DOIs
Publication statusPublished - 2015 Jan 1

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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