Isopropyl carbamates derived from benzylamines provide isoindolinones by treatment with phosphorus pentoxide at room temperature. Utility of this Bischler-Napieralski-type cyclization and a new mechanism involving a carbamoyl cation for rationalization of this smooth conversion are discussed.
|Number of pages||4|
|Publication status||Published - 2014 Mar 17|
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry