Smooth-tip dielectrophoresis based tweesers for single liposome handling

Taiga Kodama, Toshihisa Osaki, Ryuji Kawano, Koki Kamiya, Norihisa Miki, Shoji Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In prior work, we reported an efficient methodology for cell-sized liposome manipulation using DEP-based tweezers [1]. In this work, we improved the tweezers that was added further precision in the liposome handling. This devise consists of a smooth-tip glass needle and a pair of thin Au-film electrodes. The smooth tip, which is fabricated by melting a finely-pulled glass needle, is able to concentrate the DEP effect. Using this tweezers, we succeeded in capturing, manipulating and positioning single giant-liposomes of various sizes. This device will become an efficient tool for handling single biological particles such as liposome-based artificial cells.

Original languageEnglish
Title of host publicationProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
PublisherChemical and Biological Microsystems Society
Pages1081-1083
Number of pages3
ISBN (Print)9780979806452
Publication statusPublished - 2012 Jan 1
Event16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan
Duration: 2012 Oct 282012 Nov 1

Publication series

NameProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

Other

Other16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
CountryJapan
CityOkinawa
Period12/10/2812/11/1

    Fingerprint

Keywords

  • Dielectrophoresis
  • Liposome
  • Single-particle handling

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

Cite this

Kodama, T., Osaki, T., Kawano, R., Kamiya, K., Miki, N., & Takeuchi, S. (2012). Smooth-tip dielectrophoresis based tweesers for single liposome handling. In Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 (pp. 1081-1083). (Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012). Chemical and Biological Microsystems Society.