Solitary hepatic lymphangioma

Report of a case

Takuya Matsumoto, Hidenori Ojima, Yuri Akishima-Fukasawa, Nobuyoshi Hiraoka, Hiroaki Onaya, Kazuaki Shimada, Yasunori Mizuguchi, Shintaro Sakurai, Toshiharu Ishii, Tomoo Kosuge, Yae Kanai

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A 52-year-old woman presented with upper abdominal pain. Abdominal ultrasonography showed a 4-cm well-defined mass containing solid and cystic components in segment IV of the liver, and contrast-enhanced T1-weighted magnetic resonance imaging revealed heterogeneous enhancement within the tumor, indicating a solid or fibrous component. There were no cystic lesions in any other organs. A partial hepatectomy was performed, based on a preoperative diagnosis of sclerosing hemangioma and biliary cystadenoma or cystadenocarcinoma. Pathologically, the tumor appeared to be a multilocular and cystic lesion lined by attenuated endothelial- like cells with no atypia. Immunohistochemistry demonstrated the endothelial-like cells to be positive for the lymphatic-specific markers D2-40, LYVE-1, and Prox-1, which proved helpful for confirming the diagnosis as solitary hepatic lymphangioma. This case is presented with details of the pathologic and radiologic findings, because solitary hepatic lymphangioma is an extremely rare tumor and no previous reports have provided details of the immunohistochemical characteristics.

Original languageEnglish
Pages (from-to)883-889
Number of pages7
JournalSurgery Today
Volume40
Issue number9
DOIs
Publication statusPublished - 2010 Sep
Externally publishedYes

Fingerprint

Lymphangioma
Liver
Endothelial Cells
Cystadenocarcinoma
Benign Fibrous Histiocytoma
Cystadenoma
Neoplasms
Naproxen
Hepatectomy
Abdominal Pain
Ultrasonography
Immunohistochemistry
Magnetic Resonance Imaging

Keywords

  • D2-40
  • Hemangioma
  • LYVE-1
  • Prox-1
  • Solitary hepatic lymphangioma

ASJC Scopus subject areas

  • Surgery

Cite this

Matsumoto, T., Ojima, H., Akishima-Fukasawa, Y., Hiraoka, N., Onaya, H., Shimada, K., ... Kanai, Y. (2010). Solitary hepatic lymphangioma: Report of a case. Surgery Today, 40(9), 883-889. https://doi.org/10.1007/s00595-010-4255-7

Solitary hepatic lymphangioma : Report of a case. / Matsumoto, Takuya; Ojima, Hidenori; Akishima-Fukasawa, Yuri; Hiraoka, Nobuyoshi; Onaya, Hiroaki; Shimada, Kazuaki; Mizuguchi, Yasunori; Sakurai, Shintaro; Ishii, Toshiharu; Kosuge, Tomoo; Kanai, Yae.

In: Surgery Today, Vol. 40, No. 9, 09.2010, p. 883-889.

Research output: Contribution to journalArticle

Matsumoto, T, Ojima, H, Akishima-Fukasawa, Y, Hiraoka, N, Onaya, H, Shimada, K, Mizuguchi, Y, Sakurai, S, Ishii, T, Kosuge, T & Kanai, Y 2010, 'Solitary hepatic lymphangioma: Report of a case', Surgery Today, vol. 40, no. 9, pp. 883-889. https://doi.org/10.1007/s00595-010-4255-7
Matsumoto T, Ojima H, Akishima-Fukasawa Y, Hiraoka N, Onaya H, Shimada K et al. Solitary hepatic lymphangioma: Report of a case. Surgery Today. 2010 Sep;40(9):883-889. https://doi.org/10.1007/s00595-010-4255-7
Matsumoto, Takuya ; Ojima, Hidenori ; Akishima-Fukasawa, Yuri ; Hiraoka, Nobuyoshi ; Onaya, Hiroaki ; Shimada, Kazuaki ; Mizuguchi, Yasunori ; Sakurai, Shintaro ; Ishii, Toshiharu ; Kosuge, Tomoo ; Kanai, Yae. / Solitary hepatic lymphangioma : Report of a case. In: Surgery Today. 2010 ; Vol. 40, No. 9. pp. 883-889.
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