Solution concentration change of picoliter-sized microdroplet reactors

Masahiro Takinoue, Hiroaki Onoe, Shoji Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We achieved solution concentration change of a picoliter-sized water-in-oil (w/o) microdroplet reactor based on elec-trofusion and hydrodynamic breakup of microdroplets in a microfluidic channel (Fig. 1). A carrier droplet changes the solution concentration of a reactor droplet by electrofusion of them, and then they are divided without changing their reaction volume before and after the fusion-fission event. We found that this system realized high-speed concentration change of the reactor droplet (< 1 s even for complete exchange of solution). We believe that this system will be useful for analysis of dynamic chemical reactions (e.g., dynamic structural change of motor proteins, enzymatic reactions, etc.).

Original languageEnglish
Title of host publication14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Pages1829-1831
Number of pages3
Publication statusPublished - 2010 Dec 1
Externally publishedYes
Event14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 - Groningen, Netherlands
Duration: 2010 Oct 32010 Oct 7

Publication series

Name14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Volume3

Other

Other14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
CountryNetherlands
CityGroningen
Period10/10/310/10/7

Keywords

  • Microdroplets
  • Microfluidics
  • Microreactors

ASJC Scopus subject areas

  • Control and Systems Engineering

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  • Cite this

    Takinoue, M., Onoe, H., & Takeuchi, S. (2010). Solution concentration change of picoliter-sized microdroplet reactors. In 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 (pp. 1829-1831). (14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010; Vol. 3).