TY - GEN
T1 - Solution concentration change of picoliter-sized microdroplet reactors
AU - Takinoue, Masahiro
AU - Onoe, Hiroaki
AU - Takeuchi, Shoji
PY - 2010/12/1
Y1 - 2010/12/1
N2 - We achieved solution concentration change of a picoliter-sized water-in-oil (w/o) microdroplet reactor based on elec-trofusion and hydrodynamic breakup of microdroplets in a microfluidic channel (Fig. 1). A carrier droplet changes the solution concentration of a reactor droplet by electrofusion of them, and then they are divided without changing their reaction volume before and after the fusion-fission event. We found that this system realized high-speed concentration change of the reactor droplet (< 1 s even for complete exchange of solution). We believe that this system will be useful for analysis of dynamic chemical reactions (e.g., dynamic structural change of motor proteins, enzymatic reactions, etc.).
AB - We achieved solution concentration change of a picoliter-sized water-in-oil (w/o) microdroplet reactor based on elec-trofusion and hydrodynamic breakup of microdroplets in a microfluidic channel (Fig. 1). A carrier droplet changes the solution concentration of a reactor droplet by electrofusion of them, and then they are divided without changing their reaction volume before and after the fusion-fission event. We found that this system realized high-speed concentration change of the reactor droplet (< 1 s even for complete exchange of solution). We believe that this system will be useful for analysis of dynamic chemical reactions (e.g., dynamic structural change of motor proteins, enzymatic reactions, etc.).
KW - Microdroplets
KW - Microfluidics
KW - Microreactors
UR - http://www.scopus.com/inward/record.url?scp=84884341508&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84884341508&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84884341508
SN - 9781618390622
T3 - 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
SP - 1829
EP - 1831
BT - 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
T2 - 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Y2 - 3 October 2010 through 7 October 2010
ER -