Solvent effect on ruthenium catalyzed dihydroxylation

Tony K.M. Shing, Eric K.W. Tam

Research output: Contribution to journalArticle

27 Citations (Scopus)


The effect of different solvents on flash dihydroxylation is compared and for the first time, the replacement of ethyl acetate with acetone was shown to give a successful, catalytic cis-dihydroxylation of the alkene moiety in cholesteryl acetate and the ruthenium catalytic cycle could be maintained by methanesulfonamide in the absence of acetonitrile.

Original languageEnglish
Pages (from-to)2179-2180
Number of pages2
JournalTetrahedron Letters
Issue number11
Publication statusPublished - 1999 Mar 12

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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