Solvent effect on ruthenium catalyzed dihydroxylation

Tony Kung Ming Shing, Eric K W Tam

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The effect of different solvents on flash dihydroxylation is compared and for the first time, the replacement of ethyl acetate with acetone was shown to give a successful, catalytic cis-dihydroxylation of the alkene moiety in cholesteryl acetate and the ruthenium catalytic cycle could be maintained by methanesulfonamide in the absence of acetonitrile.

Original languageEnglish
Pages (from-to)2179-2180
Number of pages2
JournalTetrahedron Letters
Volume40
Issue number11
DOIs
Publication statusPublished - 1999 Mar 12
Externally publishedYes

Fingerprint

Ruthenium
Alkenes
Acetone
acetonitrile
cholesterol acetate
methanesulfonamide
ethyl acetate

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Solvent effect on ruthenium catalyzed dihydroxylation. / Shing, Tony Kung Ming; Tam, Eric K W.

In: Tetrahedron Letters, Vol. 40, No. 11, 12.03.1999, p. 2179-2180.

Research output: Contribution to journalArticle

Shing, Tony Kung Ming ; Tam, Eric K W. / Solvent effect on ruthenium catalyzed dihydroxylation. In: Tetrahedron Letters. 1999 ; Vol. 40, No. 11. pp. 2179-2180.
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