Spatially selective T2 and T2* measurement with line-scan echo-planar spectroscopic imaging

Nan Kuei Chen, Koichi Oshio, Lawrence P. Panych, Frank J. Rybicki, Robert V. Mulkern

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Line-scan echo planar spectroscopic imaging (LSEPSI) is applied to quickly measure the T2 and T2* relaxation time constants in pre-selected 2D or 3D regions. Results from brain imaging studies at 3 T suggest that the proposed method may prove valuable for both basic research (e.g., quantifying the changes of T2/T2* values in functional MRI with blood oxygenation level-dependent contrast) and clinical studies (e.g., measuring the T2′ shortening due to iron deposition). The proposed spatially selective T2 and T2* mapping technique is especially well suited for studies, where T2/T2* quantification needs to be performed dynamically in a pre-selected 2D or 3D region.

Original languageEnglish
Pages (from-to)90-96
Number of pages7
JournalJournal of Magnetic Resonance
Volume171
Issue number1
DOIs
Publication statusPublished - 2004 Nov

Fingerprint

Echo-Planar Imaging
oxygenation
Neuroimaging
time constant
blood
brain
echoes
Iron
relaxation time
Magnetic Resonance Imaging
Imaging techniques
iron
Oxygenation
Research
Relaxation time
Brain
Blood
Clinical Studies

Keywords

  • Echo-planar spectroscopic imaging
  • fMRI
  • Line-scan
  • T2 mapping

ASJC Scopus subject areas

  • Molecular Biology
  • Physical and Theoretical Chemistry
  • Spectroscopy
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics

Cite this

Spatially selective T2 and T2* measurement with line-scan echo-planar spectroscopic imaging. / Chen, Nan Kuei; Oshio, Koichi; Panych, Lawrence P.; Rybicki, Frank J.; Mulkern, Robert V.

In: Journal of Magnetic Resonance, Vol. 171, No. 1, 11.2004, p. 90-96.

Research output: Contribution to journalArticle

Chen, Nan Kuei ; Oshio, Koichi ; Panych, Lawrence P. ; Rybicki, Frank J. ; Mulkern, Robert V. / Spatially selective T2 and T2* measurement with line-scan echo-planar spectroscopic imaging. In: Journal of Magnetic Resonance. 2004 ; Vol. 171, No. 1. pp. 90-96.
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