TY - GEN
T1 - Specially patterned and aligned neural bundle formed by neural stem cell microfibers
AU - Kato-Negishi, Midori
AU - Onoe, Hiroaki
AU - Takeuchi, Shoji
PY - 2013/4/2
Y1 - 2013/4/2
N2 - This paper describes preliminary result of a specially patterned and aligned neural bundle formed by neural stem cell (NSC) microfibers for neural transplantation. The NSC microfibers are made by core-shell hydrogel microfiber encapsulating mouse NSCs. We developed a technique to align microfibers in a straight line and arrange the fibers in special patterns. Using this technique, we formed a neural bundle covered with neural-supporting cells (glial cell fibers). We believe that our neural bundle would be an extremely effective tool for tissue engineering to fabricate macroscopic neural tissue constructs and medical transplantation in neurodegenerative diseases: cerebral infarction, stroke, spinal cord injury and peripheral nerve injury.
AB - This paper describes preliminary result of a specially patterned and aligned neural bundle formed by neural stem cell (NSC) microfibers for neural transplantation. The NSC microfibers are made by core-shell hydrogel microfiber encapsulating mouse NSCs. We developed a technique to align microfibers in a straight line and arrange the fibers in special patterns. Using this technique, we formed a neural bundle covered with neural-supporting cells (glial cell fibers). We believe that our neural bundle would be an extremely effective tool for tissue engineering to fabricate macroscopic neural tissue constructs and medical transplantation in neurodegenerative diseases: cerebral infarction, stroke, spinal cord injury and peripheral nerve injury.
UR - http://www.scopus.com/inward/record.url?scp=84875430613&partnerID=8YFLogxK
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U2 - 10.1109/MEMSYS.2013.6474194
DO - 10.1109/MEMSYS.2013.6474194
M3 - Conference contribution
AN - SCOPUS:84875430613
SN - 9781467356558
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 130
EP - 132
BT - IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
T2 - IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Y2 - 20 January 2013 through 24 January 2013
ER -