Specially patterned and aligned neural bundle formed by neural stem cell microfibers

Midori Kato-Negishi, Hiroaki Onoe, Shoji Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

This paper describes preliminary result of a specially patterned and aligned neural bundle formed by neural stem cell (NSC) microfibers for neural transplantation. The NSC microfibers are made by core-shell hydrogel microfiber encapsulating mouse NSCs. We developed a technique to align microfibers in a straight line and arrange the fibers in special patterns. Using this technique, we formed a neural bundle covered with neural-supporting cells (glial cell fibers). We believe that our neural bundle would be an extremely effective tool for tissue engineering to fabricate macroscopic neural tissue constructs and medical transplantation in neurodegenerative diseases: cerebral infarction, stroke, spinal cord injury and peripheral nerve injury.

Original languageEnglish
Title of host publicationIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Pages130-132
Number of pages3
DOIs
Publication statusPublished - 2013 Apr 2
Externally publishedYes
EventIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 - Taipei, Taiwan, Province of China
Duration: 2013 Jan 202013 Jan 24

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)1084-6999

Other

OtherIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
CountryTaiwan, Province of China
CityTaipei
Period13/1/2013/1/24

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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  • Cite this

    Kato-Negishi, M., Onoe, H., & Takeuchi, S. (2013). Specially patterned and aligned neural bundle formed by neural stem cell microfibers. In IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 (pp. 130-132). [6474194] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2013.6474194