Specially patterned and aligned neural bundle formed by neural stem cell microfibers

Midori Kato-Negishi, Hiroaki Onoe, Shoji Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

This paper describes preliminary result of a specially patterned and aligned neural bundle formed by neural stem cell (NSC) microfibers for neural transplantation. The NSC microfibers are made by core-shell hydrogel microfiber encapsulating mouse NSCs. We developed a technique to align microfibers in a straight line and arrange the fibers in special patterns. Using this technique, we formed a neural bundle covered with neural-supporting cells (glial cell fibers). We believe that our neural bundle would be an extremely effective tool for tissue engineering to fabricate macroscopic neural tissue constructs and medical transplantation in neurodegenerative diseases: cerebral infarction, stroke, spinal cord injury and peripheral nerve injury.

Original languageEnglish
Title of host publicationProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Pages130-132
Number of pages3
DOIs
Publication statusPublished - 2013
Externally publishedYes
EventIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 - Taipei, Taiwan, Province of China
Duration: 2013 Jan 202013 Jan 24

Other

OtherIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
CountryTaiwan, Province of China
CityTaipei
Period13/1/2013/1/24

Fingerprint

microfibers
stem cells
Stem cells
bundles
Neurodegenerative diseases
transplantation
Fibers
Hydrogel
Tissue engineering
Hydrogels
spinal cord injuries
infarction
Tissue
encapsulating
fibers
tissue engineering
nerves
strokes
mice
cells

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Mechanical Engineering
  • Condensed Matter Physics
  • Electronic, Optical and Magnetic Materials

Cite this

Kato-Negishi, M., Onoe, H., & Takeuchi, S. (2013). Specially patterned and aligned neural bundle formed by neural stem cell microfibers. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) (pp. 130-132). [6474194] https://doi.org/10.1109/MEMSYS.2013.6474194

Specially patterned and aligned neural bundle formed by neural stem cell microfibers. / Kato-Negishi, Midori; Onoe, Hiroaki; Takeuchi, Shoji.

Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2013. p. 130-132 6474194.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kato-Negishi, M, Onoe, H & Takeuchi, S 2013, Specially patterned and aligned neural bundle formed by neural stem cell microfibers. in Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)., 6474194, pp. 130-132, IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013, Taipei, Taiwan, Province of China, 13/1/20. https://doi.org/10.1109/MEMSYS.2013.6474194
Kato-Negishi M, Onoe H, Takeuchi S. Specially patterned and aligned neural bundle formed by neural stem cell microfibers. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2013. p. 130-132. 6474194 https://doi.org/10.1109/MEMSYS.2013.6474194
Kato-Negishi, Midori ; Onoe, Hiroaki ; Takeuchi, Shoji. / Specially patterned and aligned neural bundle formed by neural stem cell microfibers. Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2013. pp. 130-132
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