Spike-triggered dendritic calcium transients depend on synaptic activity in the cricket giant interneurons

Yoshichika Baba, Hiroto Ogawa, Kotaro Oka

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The relationship between electrical activity and spike-induced Ca2+ increases in dendrites was investigated in the identified wind-sensitive giant interneurons in the cricket. We applied a high-speed Ca2+ imaging technique to the giant interneurons, and succeeded in recording the transient Ca2+ increases (Ca2+ transients) induced by a single action potential, which was evoked by presynaptic stimulus to the sensory neurons. The dendritic Ca2+ transients evoked by a pair of action potentials accumulated when spike intervals were shorter than 100 ms. The amplitude of the Ca2+ transients induced by a train of spikes depended on the number of action potentials. When stimulation pulses evoking the same numbers of action potentials were separately applied to the ipsi- or contra-lateral cercal sensory nerves, the dendritic Ca2+ transients induced by these presynaptic stimuli were different in their amplitude. Furthermore, the side of presynaptic stimulation that evoked larger Ca2+ transients depended on the location of the recorded dendritic regions. This result means that the spike-triggered Ca2+ transients in dendrites depend on postsynaptic activity. It is proposed that Ca2+ entry through voltage-dependent Ca2+ channels activated by the action potentials will be enhanced by excitatory synaptic inputs at the dendrites in the cricket giant interneurons.

Original languageEnglish
Pages (from-to)234-244
Number of pages11
JournalJournal of Neurobiology
Volume50
Issue number3
DOIs
Publication statusPublished - 2002 Feb 15

Keywords

  • Ca imaging
  • Cricket
  • Dendrite
  • Giant interneuron
  • Oregon Green 488 BAPTA-1

ASJC Scopus subject areas

  • Neuroscience(all)
  • Cellular and Molecular Neuroscience

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