Abstract
Lipid characterization of bone marrow in vivo with proton magnetic resonance spectroscopy was performed using Spin-Echo Planar Spectroscopic Imaging sequences. The methods are shown capable of rapidly generating two- dimensional chemical shift imaging data sets suitable for measuring lipid indices that reflect unsaturation levels among triglycerides, as demonstrated in oil phantoms and bone marrow from a healthy volunteer. The volume coverage, spatial resolution, acquisition speed, and spectral characteristics of Spin-Echo Planar Spectroscopic Imaging should make it attractive for clinical studies of diseases affecting normal lipid chemical composition.
Original language | English |
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Pages (from-to) | 1203-1210 |
Number of pages | 8 |
Journal | Magnetic Resonance Imaging |
Volume | 17 |
Issue number | 8 |
DOIs | |
Publication status | Published - 1999 Oct |
Externally published | Yes |
Keywords
- Echo planar imaging (EPI)
- H MRS
- Lipids
ASJC Scopus subject areas
- Biophysics
- Biomedical Engineering
- Radiology Nuclear Medicine and imaging