Spinal fractures in diffuse idiopathic skeletal hyperostosis: Advantages of percutaneous pedicle screw fixation

Eijiro Okada, Yuta Shiono, Mitsuhiro Nishida, Yuichiro Mima, Haruki Funao, Kentaro Shimizu, Masanori Kato, Kentaro Fukuda, Nobuyuki Fujita, Mitsuru Yagi, Narihito Nagoshi, Osahiko Tsuji, Ken Ishii, Masaya Nakamura, Morio Matsumoto, Koota Watanabe

Research output: Contribution to journalArticle

Abstract

PURPOSE: To validate the effectiveness of percutaneous pedicle screw (PPS) fixation for spinal fractures associated with diffuse idiopathic skeletal hyperostosis (DISH) by comparing surgical outcomes for PPS fixation and conventional open posterior fixation. Patients with DISH are vulnerable to unstable spinal fractures caused by trivial trauma, and these fractures have high rates of delayed paralysis, postoperative complications, and mortality. METHODS: This retrospective study assessed surgical outcomes for 16 patients with DISH (12 men; mean age 76.1 ± 9.4 years) who underwent PPS fixation for spinal fractures (pedicle screw (PS) group), and for a control group of 25 patients with DISH (18 men; mean age 77.9 ± 9.9 years) who underwent conventional open fixation (O group) at our affiliated hospitals from 2007 to 2017. We evaluated the preoperative physical condition (American Society of Anesthesiologists (ASA) classification), neurological status (Frankel grade), and improvement after surgery, fusion length, operating time, estimated blood loss, and perioperative complications. RESULTS: Preoperatively, the PS group consisted of one ASA-1 patient, eight ASA-2 patients, six ASA-3 patients, and one ASA-4 patient; by Frankel grade, there were 2 grade B patients, 13 grade C, 4 grade D, and 6 grade E patients. The O group had 2 ASA-1 patients, 13 ASA-2, 9 ASA-3, and 1 ASA-4 patients. Frankel grades in the O group reflected severe neurological deficits, with 3 grade C patients, 2 grade D, and 11 grade E ( p = 0.032) patients. The two groups had similar rates of neurological improvement (33.3% of PS and 40.0% of O patients; p = 0.410) and mean fusion length (PS 5.1 ± 0.8 segments; O 4.9 ± 1.2). The mean operating time and estimated blood loss were 168.1 ± 46.7 min and 133.9 ± 116.5 g, respectively, in the PS group, and 224.6 ± 49.8 min and 499.9 ± 368.5 g in the O group. Three O-group patients died of hypovolemic shock, respiratory failure, and pneumonia, respectively, within a year of surgery. CONCLUSION: Conventional open posterior fixation and PPS fixation for DISH-related spinal fractures were similar in fusion length and neurological improvement. However, PPS fixation was less invasive and had lower complication rates.

Original languageEnglish
JournalJournal of orthopaedic surgery (Hong Kong)
Volume27
Issue number2
DOIs
Publication statusPublished - 2019 May 1

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Diffuse Idiopathic Skeletal Hyperostosis
Spinal Fractures
Pedicle Screws
Anesthesiologists

Keywords

  • ankylosing spinal disorder
  • diffuse idiopathic skeletal hyperostosis
  • flowing ossification
  • percutaneous pedicle screw fixation
  • spinal fracture
  • surgical outcomes

ASJC Scopus subject areas

  • Surgery

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Spinal fractures in diffuse idiopathic skeletal hyperostosis : Advantages of percutaneous pedicle screw fixation. / Okada, Eijiro; Shiono, Yuta; Nishida, Mitsuhiro; Mima, Yuichiro; Funao, Haruki; Shimizu, Kentaro; Kato, Masanori; Fukuda, Kentaro; Fujita, Nobuyuki; Yagi, Mitsuru; Nagoshi, Narihito; Tsuji, Osahiko; Ishii, Ken; Nakamura, Masaya; Matsumoto, Morio; Watanabe, Koota.

In: Journal of orthopaedic surgery (Hong Kong), Vol. 27, No. 2, 01.05.2019.

Research output: Contribution to journalArticle

Okada, Eijiro ; Shiono, Yuta ; Nishida, Mitsuhiro ; Mima, Yuichiro ; Funao, Haruki ; Shimizu, Kentaro ; Kato, Masanori ; Fukuda, Kentaro ; Fujita, Nobuyuki ; Yagi, Mitsuru ; Nagoshi, Narihito ; Tsuji, Osahiko ; Ishii, Ken ; Nakamura, Masaya ; Matsumoto, Morio ; Watanabe, Koota. / Spinal fractures in diffuse idiopathic skeletal hyperostosis : Advantages of percutaneous pedicle screw fixation. In: Journal of orthopaedic surgery (Hong Kong). 2019 ; Vol. 27, No. 2.
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abstract = "PURPOSE: To validate the effectiveness of percutaneous pedicle screw (PPS) fixation for spinal fractures associated with diffuse idiopathic skeletal hyperostosis (DISH) by comparing surgical outcomes for PPS fixation and conventional open posterior fixation. Patients with DISH are vulnerable to unstable spinal fractures caused by trivial trauma, and these fractures have high rates of delayed paralysis, postoperative complications, and mortality. METHODS: This retrospective study assessed surgical outcomes for 16 patients with DISH (12 men; mean age 76.1 ± 9.4 years) who underwent PPS fixation for spinal fractures (pedicle screw (PS) group), and for a control group of 25 patients with DISH (18 men; mean age 77.9 ± 9.9 years) who underwent conventional open fixation (O group) at our affiliated hospitals from 2007 to 2017. We evaluated the preoperative physical condition (American Society of Anesthesiologists (ASA) classification), neurological status (Frankel grade), and improvement after surgery, fusion length, operating time, estimated blood loss, and perioperative complications. RESULTS: Preoperatively, the PS group consisted of one ASA-1 patient, eight ASA-2 patients, six ASA-3 patients, and one ASA-4 patient; by Frankel grade, there were 2 grade B patients, 13 grade C, 4 grade D, and 6 grade E patients. The O group had 2 ASA-1 patients, 13 ASA-2, 9 ASA-3, and 1 ASA-4 patients. Frankel grades in the O group reflected severe neurological deficits, with 3 grade C patients, 2 grade D, and 11 grade E ( p = 0.032) patients. The two groups had similar rates of neurological improvement (33.3{\%} of PS and 40.0{\%} of O patients; p = 0.410) and mean fusion length (PS 5.1 ± 0.8 segments; O 4.9 ± 1.2). The mean operating time and estimated blood loss were 168.1 ± 46.7 min and 133.9 ± 116.5 g, respectively, in the PS group, and 224.6 ± 49.8 min and 499.9 ± 368.5 g in the O group. Three O-group patients died of hypovolemic shock, respiratory failure, and pneumonia, respectively, within a year of surgery. CONCLUSION: Conventional open posterior fixation and PPS fixation for DISH-related spinal fractures were similar in fusion length and neurological improvement. However, PPS fixation was less invasive and had lower complication rates.",
keywords = "ankylosing spinal disorder, diffuse idiopathic skeletal hyperostosis, flowing ossification, percutaneous pedicle screw fixation, spinal fracture, surgical outcomes",
author = "Eijiro Okada and Yuta Shiono and Mitsuhiro Nishida and Yuichiro Mima and Haruki Funao and Kentaro Shimizu and Masanori Kato and Kentaro Fukuda and Nobuyuki Fujita and Mitsuru Yagi and Narihito Nagoshi and Osahiko Tsuji and Ken Ishii and Masaya Nakamura and Morio Matsumoto and Koota Watanabe",
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language = "English",
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T1 - Spinal fractures in diffuse idiopathic skeletal hyperostosis

T2 - Advantages of percutaneous pedicle screw fixation

AU - Okada, Eijiro

AU - Shiono, Yuta

AU - Nishida, Mitsuhiro

AU - Mima, Yuichiro

AU - Funao, Haruki

AU - Shimizu, Kentaro

AU - Kato, Masanori

AU - Fukuda, Kentaro

AU - Fujita, Nobuyuki

AU - Yagi, Mitsuru

AU - Nagoshi, Narihito

AU - Tsuji, Osahiko

AU - Ishii, Ken

AU - Nakamura, Masaya

AU - Matsumoto, Morio

AU - Watanabe, Koota

PY - 2019/5/1

Y1 - 2019/5/1

N2 - PURPOSE: To validate the effectiveness of percutaneous pedicle screw (PPS) fixation for spinal fractures associated with diffuse idiopathic skeletal hyperostosis (DISH) by comparing surgical outcomes for PPS fixation and conventional open posterior fixation. Patients with DISH are vulnerable to unstable spinal fractures caused by trivial trauma, and these fractures have high rates of delayed paralysis, postoperative complications, and mortality. METHODS: This retrospective study assessed surgical outcomes for 16 patients with DISH (12 men; mean age 76.1 ± 9.4 years) who underwent PPS fixation for spinal fractures (pedicle screw (PS) group), and for a control group of 25 patients with DISH (18 men; mean age 77.9 ± 9.9 years) who underwent conventional open fixation (O group) at our affiliated hospitals from 2007 to 2017. We evaluated the preoperative physical condition (American Society of Anesthesiologists (ASA) classification), neurological status (Frankel grade), and improvement after surgery, fusion length, operating time, estimated blood loss, and perioperative complications. RESULTS: Preoperatively, the PS group consisted of one ASA-1 patient, eight ASA-2 patients, six ASA-3 patients, and one ASA-4 patient; by Frankel grade, there were 2 grade B patients, 13 grade C, 4 grade D, and 6 grade E patients. The O group had 2 ASA-1 patients, 13 ASA-2, 9 ASA-3, and 1 ASA-4 patients. Frankel grades in the O group reflected severe neurological deficits, with 3 grade C patients, 2 grade D, and 11 grade E ( p = 0.032) patients. The two groups had similar rates of neurological improvement (33.3% of PS and 40.0% of O patients; p = 0.410) and mean fusion length (PS 5.1 ± 0.8 segments; O 4.9 ± 1.2). The mean operating time and estimated blood loss were 168.1 ± 46.7 min and 133.9 ± 116.5 g, respectively, in the PS group, and 224.6 ± 49.8 min and 499.9 ± 368.5 g in the O group. Three O-group patients died of hypovolemic shock, respiratory failure, and pneumonia, respectively, within a year of surgery. CONCLUSION: Conventional open posterior fixation and PPS fixation for DISH-related spinal fractures were similar in fusion length and neurological improvement. However, PPS fixation was less invasive and had lower complication rates.

AB - PURPOSE: To validate the effectiveness of percutaneous pedicle screw (PPS) fixation for spinal fractures associated with diffuse idiopathic skeletal hyperostosis (DISH) by comparing surgical outcomes for PPS fixation and conventional open posterior fixation. Patients with DISH are vulnerable to unstable spinal fractures caused by trivial trauma, and these fractures have high rates of delayed paralysis, postoperative complications, and mortality. METHODS: This retrospective study assessed surgical outcomes for 16 patients with DISH (12 men; mean age 76.1 ± 9.4 years) who underwent PPS fixation for spinal fractures (pedicle screw (PS) group), and for a control group of 25 patients with DISH (18 men; mean age 77.9 ± 9.9 years) who underwent conventional open fixation (O group) at our affiliated hospitals from 2007 to 2017. We evaluated the preoperative physical condition (American Society of Anesthesiologists (ASA) classification), neurological status (Frankel grade), and improvement after surgery, fusion length, operating time, estimated blood loss, and perioperative complications. RESULTS: Preoperatively, the PS group consisted of one ASA-1 patient, eight ASA-2 patients, six ASA-3 patients, and one ASA-4 patient; by Frankel grade, there were 2 grade B patients, 13 grade C, 4 grade D, and 6 grade E patients. The O group had 2 ASA-1 patients, 13 ASA-2, 9 ASA-3, and 1 ASA-4 patients. Frankel grades in the O group reflected severe neurological deficits, with 3 grade C patients, 2 grade D, and 11 grade E ( p = 0.032) patients. The two groups had similar rates of neurological improvement (33.3% of PS and 40.0% of O patients; p = 0.410) and mean fusion length (PS 5.1 ± 0.8 segments; O 4.9 ± 1.2). The mean operating time and estimated blood loss were 168.1 ± 46.7 min and 133.9 ± 116.5 g, respectively, in the PS group, and 224.6 ± 49.8 min and 499.9 ± 368.5 g in the O group. Three O-group patients died of hypovolemic shock, respiratory failure, and pneumonia, respectively, within a year of surgery. CONCLUSION: Conventional open posterior fixation and PPS fixation for DISH-related spinal fractures were similar in fusion length and neurological improvement. However, PPS fixation was less invasive and had lower complication rates.

KW - ankylosing spinal disorder

KW - diffuse idiopathic skeletal hyperostosis

KW - flowing ossification

KW - percutaneous pedicle screw fixation

KW - spinal fracture

KW - surgical outcomes

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