TY - JOUR
T1 - Spontaneous massive hemorrhage within a malignant tumor of the liver
T2 - Diagnostic features in sonography and CT
AU - Aoki, Kazunori
AU - Takayasu, Kenichi
AU - Muramatsu, Yukio
AU - Moriyama, Noriyuki
AU - Mizuguchi, Yasunori
AU - Sakamoto, Michiie
AU - Hirohashi, Setsuo
N1 - Funding Information:
Chiba University School of Medicine for his review of the manuscript. The study was supported in part by a Grant-in-Aid for Cancer Research from the Ministry of Health and Welfare.
PY - 1991/10
Y1 - 1991/10
N2 - Computed tomography (CT) and sonography performed on four patients with histopathologically proven massive intratumoral hemorrhages in the liver were compared with pathological findings. Unenhanced CT showed a round low-density mass, and enhanced CT produced slight enhancements in the peripheral portions of the masses in two patients which corresponded to histopathologically viable cancerous portions. In contrast, sonography showed multilocular cystic masses with variously shaped septa, assuming a honeycomb appearance. Histopathologically, the septa were made up of blood clots with or without granulation tissue, scar and viable tumor, and the cystic spaces were filled with exudate and erythrocytes. Combined study by CT and sonography could be useful in differentiating massive hemorrhagic malignancies from cystic and necrotic masses and/or simple hemorrhagic lesions. The danger of malignant tumors with massive hemorrhage possibly being diagnosed as benign lesions, such as hematomas and abscesses, is also stressed.
AB - Computed tomography (CT) and sonography performed on four patients with histopathologically proven massive intratumoral hemorrhages in the liver were compared with pathological findings. Unenhanced CT showed a round low-density mass, and enhanced CT produced slight enhancements in the peripheral portions of the masses in two patients which corresponded to histopathologically viable cancerous portions. In contrast, sonography showed multilocular cystic masses with variously shaped septa, assuming a honeycomb appearance. Histopathologically, the septa were made up of blood clots with or without granulation tissue, scar and viable tumor, and the cystic spaces were filled with exudate and erythrocytes. Combined study by CT and sonography could be useful in differentiating massive hemorrhagic malignancies from cystic and necrotic masses and/or simple hemorrhagic lesions. The danger of malignant tumors with massive hemorrhage possibly being diagnosed as benign lesions, such as hematomas and abscesses, is also stressed.
KW - Computed tomography
KW - Liver hemorrhage
KW - Liver neoplasms
KW - Sonography
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M3 - Article
C2 - 1753417
AN - SCOPUS:0026232639
SN - 0368-2811
VL - 21
SP - 366
EP - 371
JO - Japanese Journal of Clinical Oncology
JF - Japanese Journal of Clinical Oncology
IS - 5
ER -
