Spontaneous regression of hepatocellular carcinoma in S4 after another tumor in S1 was chemoembolized

Tetsuro Takayama, Shinichiro Tada, Shigeo Yoshizawa, Hidetsugu Saito, Toshifumi Hibi

Research output: Contribution to journalArticle

Abstract

An HCV-infected 77 year-old female with a history of blood transfusion when operated for disk herniation in 1960 developed multiple hepatocellular carcinoma in 2003: one in S1 and another in S4. Considering the impaired function of her cirrhotic liver, we planned to undertake transarterial chemoembolization (TAE) first for only the S1 tumor and later for the S4 tumor. One day, about 4 weeks after TAE was done successfully for her S1 tumor, she suddenly suffered from high fever and a sharp increase in transaminases. On the following day, we performed dynamic CT scanning and found that the S4 tumor had lost its tumor-specific enhancement, suggesting an extensive spontaneous necrosis of this tumor. The S4 tumor continued to regress thereafter. This was a rare event with almost no report in literature to our knowledge, particularly in that we could trace the time course of tumor-regression.

Original languageEnglish
Pages (from-to)78-84
Number of pages7
JournalActa Hepatologica Japonica
Volume46
Issue number2
DOIs
Publication statusPublished - 2005

Fingerprint

Hepatocellular Carcinoma
Neoplasms
Transaminases
Blood Transfusion
Fever
Necrosis
Liver

ASJC Scopus subject areas

  • Hepatology

Cite this

Spontaneous regression of hepatocellular carcinoma in S4 after another tumor in S1 was chemoembolized. / Takayama, Tetsuro; Tada, Shinichiro; Yoshizawa, Shigeo; Saito, Hidetsugu; Hibi, Toshifumi.

In: Acta Hepatologica Japonica, Vol. 46, No. 2, 2005, p. 78-84.

Research output: Contribution to journalArticle

Takayama, Tetsuro ; Tada, Shinichiro ; Yoshizawa, Shigeo ; Saito, Hidetsugu ; Hibi, Toshifumi. / Spontaneous regression of hepatocellular carcinoma in S4 after another tumor in S1 was chemoembolized. In: Acta Hepatologica Japonica. 2005 ; Vol. 46, No. 2. pp. 78-84.
@article{dd4f0c2e992b4deaa6fec64971d579cf,
title = "Spontaneous regression of hepatocellular carcinoma in S4 after another tumor in S1 was chemoembolized",
abstract = "An HCV-infected 77 year-old female with a history of blood transfusion when operated for disk herniation in 1960 developed multiple hepatocellular carcinoma in 2003: one in S1 and another in S4. Considering the impaired function of her cirrhotic liver, we planned to undertake transarterial chemoembolization (TAE) first for only the S1 tumor and later for the S4 tumor. One day, about 4 weeks after TAE was done successfully for her S1 tumor, she suddenly suffered from high fever and a sharp increase in transaminases. On the following day, we performed dynamic CT scanning and found that the S4 tumor had lost its tumor-specific enhancement, suggesting an extensive spontaneous necrosis of this tumor. The S4 tumor continued to regress thereafter. This was a rare event with almost no report in literature to our knowledge, particularly in that we could trace the time course of tumor-regression.",
author = "Tetsuro Takayama and Shinichiro Tada and Shigeo Yoshizawa and Hidetsugu Saito and Toshifumi Hibi",
year = "2005",
doi = "10.2957/kanzo.46.78",
language = "English",
volume = "46",
pages = "78--84",
journal = "Acta Hepatologica Japonica",
issn = "0451-4203",
publisher = "Japan Society of Hepatology",
number = "2",

}

TY - JOUR

T1 - Spontaneous regression of hepatocellular carcinoma in S4 after another tumor in S1 was chemoembolized

AU - Takayama, Tetsuro

AU - Tada, Shinichiro

AU - Yoshizawa, Shigeo

AU - Saito, Hidetsugu

AU - Hibi, Toshifumi

PY - 2005

Y1 - 2005

N2 - An HCV-infected 77 year-old female with a history of blood transfusion when operated for disk herniation in 1960 developed multiple hepatocellular carcinoma in 2003: one in S1 and another in S4. Considering the impaired function of her cirrhotic liver, we planned to undertake transarterial chemoembolization (TAE) first for only the S1 tumor and later for the S4 tumor. One day, about 4 weeks after TAE was done successfully for her S1 tumor, she suddenly suffered from high fever and a sharp increase in transaminases. On the following day, we performed dynamic CT scanning and found that the S4 tumor had lost its tumor-specific enhancement, suggesting an extensive spontaneous necrosis of this tumor. The S4 tumor continued to regress thereafter. This was a rare event with almost no report in literature to our knowledge, particularly in that we could trace the time course of tumor-regression.

AB - An HCV-infected 77 year-old female with a history of blood transfusion when operated for disk herniation in 1960 developed multiple hepatocellular carcinoma in 2003: one in S1 and another in S4. Considering the impaired function of her cirrhotic liver, we planned to undertake transarterial chemoembolization (TAE) first for only the S1 tumor and later for the S4 tumor. One day, about 4 weeks after TAE was done successfully for her S1 tumor, she suddenly suffered from high fever and a sharp increase in transaminases. On the following day, we performed dynamic CT scanning and found that the S4 tumor had lost its tumor-specific enhancement, suggesting an extensive spontaneous necrosis of this tumor. The S4 tumor continued to regress thereafter. This was a rare event with almost no report in literature to our knowledge, particularly in that we could trace the time course of tumor-regression.

UR - http://www.scopus.com/inward/record.url?scp=15544387582&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=15544387582&partnerID=8YFLogxK

U2 - 10.2957/kanzo.46.78

DO - 10.2957/kanzo.46.78

M3 - Article

VL - 46

SP - 78

EP - 84

JO - Acta Hepatologica Japonica

JF - Acta Hepatologica Japonica

SN - 0451-4203

IS - 2

ER -