Stability of the microdroplets for portable biosensor

Yusuke Izawa, Toshihisa Osaki, Koki Kamiya, Satoshi Fujii, Norihisa Miki, Shoji Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper highlights the behavior of microdroplets used for portable biosensors. Microdroplets have been applied for various Lab-on-a-chip applications, in which portability/wearable is becoming a trend word. However, the resonance (sloshing phenomena) of the microdroplets could be an issue. For example, bilayer lipid membrane, fragile characteristics due to its thickness of 5 nm, easily ruptures by jiggling. We therefore prepared various dimensions of droplets by changing the well shape, and examined the resulting waves depending on the vibration frequency between 20 and 100 Hz, including daily life frequencies. Moreover, we investigated an influence of surface coating of the wells by the same tests. The results of the first examination showed that the sloshing was effectively suppressed by reducing the well length along the vibration axis. We also found that the sloshing was suppressed by reducing surface energy of the microwells. We succeeded in clarifying the characteristics of microdroplets at the vibration in daily life frequency, which will be useful information for development of portable biosensors.

Original languageEnglish
Title of host publication2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1918-1921
Number of pages4
Volume2016-October
ISBN (Electronic)9781457702204
DOIs
Publication statusPublished - 2016 Oct 13
Event38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 - Orlando, United States
Duration: 2016 Aug 162016 Aug 20

Other

Other38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
CountryUnited States
CityOrlando
Period16/8/1616/8/20

Fingerprint

Liquid sloshing
Biosensing Techniques
Vibration
Biosensors
Lab-on-a-chip
Lipid bilayers
Lipid Bilayers
Membrane Lipids
Interfacial energy
Rupture
Coatings

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Izawa, Y., Osaki, T., Kamiya, K., Fujii, S., Miki, N., & Takeuchi, S. (2016). Stability of the microdroplets for portable biosensor. In 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 (Vol. 2016-October, pp. 1918-1921). [7591097] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2016.7591097

Stability of the microdroplets for portable biosensor. / Izawa, Yusuke; Osaki, Toshihisa; Kamiya, Koki; Fujii, Satoshi; Miki, Norihisa; Takeuchi, Shoji.

2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Vol. 2016-October Institute of Electrical and Electronics Engineers Inc., 2016. p. 1918-1921 7591097.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Izawa, Y, Osaki, T, Kamiya, K, Fujii, S, Miki, N & Takeuchi, S 2016, Stability of the microdroplets for portable biosensor. in 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. vol. 2016-October, 7591097, Institute of Electrical and Electronics Engineers Inc., pp. 1918-1921, 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016, Orlando, United States, 16/8/16. https://doi.org/10.1109/EMBC.2016.7591097
Izawa Y, Osaki T, Kamiya K, Fujii S, Miki N, Takeuchi S. Stability of the microdroplets for portable biosensor. In 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Vol. 2016-October. Institute of Electrical and Electronics Engineers Inc. 2016. p. 1918-1921. 7591097 https://doi.org/10.1109/EMBC.2016.7591097
Izawa, Yusuke ; Osaki, Toshihisa ; Kamiya, Koki ; Fujii, Satoshi ; Miki, Norihisa ; Takeuchi, Shoji. / Stability of the microdroplets for portable biosensor. 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Vol. 2016-October Institute of Electrical and Electronics Engineers Inc., 2016. pp. 1918-1921
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