TY - GEN
T1 - Stability of the microdroplets for portable biosensor
AU - Izawa, Yusuke
AU - Osaki, Toshihisa
AU - Kamiya, Koki
AU - Fujii, Satoshi
AU - Miki, Norihisa
AU - Takeuchi, Shoji
N1 - Publisher Copyright:
© 2016 IEEE.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2016/10/13
Y1 - 2016/10/13
N2 - This paper highlights the behavior of microdroplets used for portable biosensors. Microdroplets have been applied for various Lab-on-a-chip applications, in which portability/wearable is becoming a trend word. However, the resonance (sloshing phenomena) of the microdroplets could be an issue. For example, bilayer lipid membrane, fragile characteristics due to its thickness of 5 nm, easily ruptures by jiggling. We therefore prepared various dimensions of droplets by changing the well shape, and examined the resulting waves depending on the vibration frequency between 20 and 100 Hz, including daily life frequencies. Moreover, we investigated an influence of surface coating of the wells by the same tests. The results of the first examination showed that the sloshing was effectively suppressed by reducing the well length along the vibration axis. We also found that the sloshing was suppressed by reducing surface energy of the microwells. We succeeded in clarifying the characteristics of microdroplets at the vibration in daily life frequency, which will be useful information for development of portable biosensors.
AB - This paper highlights the behavior of microdroplets used for portable biosensors. Microdroplets have been applied for various Lab-on-a-chip applications, in which portability/wearable is becoming a trend word. However, the resonance (sloshing phenomena) of the microdroplets could be an issue. For example, bilayer lipid membrane, fragile characteristics due to its thickness of 5 nm, easily ruptures by jiggling. We therefore prepared various dimensions of droplets by changing the well shape, and examined the resulting waves depending on the vibration frequency between 20 and 100 Hz, including daily life frequencies. Moreover, we investigated an influence of surface coating of the wells by the same tests. The results of the first examination showed that the sloshing was effectively suppressed by reducing the well length along the vibration axis. We also found that the sloshing was suppressed by reducing surface energy of the microwells. We succeeded in clarifying the characteristics of microdroplets at the vibration in daily life frequency, which will be useful information for development of portable biosensors.
UR - http://www.scopus.com/inward/record.url?scp=85009062783&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85009062783&partnerID=8YFLogxK
U2 - 10.1109/EMBC.2016.7591097
DO - 10.1109/EMBC.2016.7591097
M3 - Conference contribution
C2 - 28268702
AN - SCOPUS:85009062783
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 1918
EP - 1921
BT - 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
Y2 - 16 August 2016 through 20 August 2016
ER -