Stereocontrolled synthesis of a highly functionalized 1,7-dioxaspiro[4.4]Nonane derivative related to antibiotic pseurotins

Shin ya Aoki, Takahiro Ohi, Kazuya Shimizu, Ryota Shiraki, Ken ichi Takao, Kin ichi Tadano

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

For a total synthesis of pseurotins, unusual heterospirocyclic antibiotics, a key intermediate (5), having a highly functionalized 1,7-dioxaspiro-[4.4]nonane structure, has been synthesized from diacetone D-glucose.

Original languageEnglish
Pages (from-to)57-61
Number of pages5
JournalHeterocycles
Volume58
Publication statusPublished - 2002 Nov 22

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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