Stereocontrolled synthesis of a highly functionalized 1,7-dioxaspiro[4.4]Nonane derivative related to antibiotic pseurotins

Shin ya Aoki, Takahiro Ohi, Kazuya Shimizu, Ryota Shiraki, Kenichi Takao, Kin ichi Tadano

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

For a total synthesis of pseurotins, unusual heterospirocyclic antibiotics, a key intermediate (5), having a highly functionalized 1,7-dioxaspiro-[4.4]nonane structure, has been synthesized from diacetone D-glucose.

Original languageEnglish
Pages (from-to)57-61
Number of pages5
JournalHeterocycles
Volume58
Publication statusPublished - 2002 Nov 22

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Anti-Bacterial Agents
Derivatives
Glucose
nonane
pseurotin
1,2-5,6-di-O-isopropylidene-D-glucofuranose

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Stereocontrolled synthesis of a highly functionalized 1,7-dioxaspiro[4.4]Nonane derivative related to antibiotic pseurotins. / Aoki, Shin ya; Ohi, Takahiro; Shimizu, Kazuya; Shiraki, Ryota; Takao, Kenichi; Tadano, Kin ichi.

In: Heterocycles, Vol. 58, 22.11.2002, p. 57-61.

Research output: Contribution to journalArticle

Aoki, Shin ya ; Ohi, Takahiro ; Shimizu, Kazuya ; Shiraki, Ryota ; Takao, Kenichi ; Tadano, Kin ichi. / Stereocontrolled synthesis of a highly functionalized 1,7-dioxaspiro[4.4]Nonane derivative related to antibiotic pseurotins. In: Heterocycles. 2002 ; Vol. 58. pp. 57-61.
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