Stereoselective total synthesis of (+)-lycoricidine

Noritaka Chida, Masami Ohtsuka, Seiichiro Ogawa

Research output: Contribution to journalArticle

87 Citations (Scopus)

Abstract

The stereoselective total synthesis of the title compound starting from D-glucose is described. The key steps in this synthesis are Ferrier rearrangement to construct the optically active cyclohexenone (C-ring), and Pd-catalyzed intramolecular Heck reaction to build the phenanthridone skeleton.

Original languageEnglish
Pages (from-to)4525-4528
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number35
DOIs
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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