Stereoselective total synthesis of (+)-lycoricidine

Noritaka Chida, Masami Ohtsuka, Seiichiro Ogawa

Research output: Contribution to journalArticle

87 Citations (Scopus)

Abstract

The stereoselective total synthesis of the title compound starting from D-glucose is described. The key steps in this synthesis are Ferrier rearrangement to construct the optically active cyclohexenone (C-ring), and Pd-catalyzed intramolecular Heck reaction to build the phenanthridone skeleton.

Original languageEnglish
Pages (from-to)4525-4528
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number35
DOIs
Publication statusPublished - 1991

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Skeleton
Glucose
lycoricidine
phenanthridone

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Stereoselective total synthesis of (+)-lycoricidine. / Chida, Noritaka; Ohtsuka, Masami; Ogawa, Seiichiro.

In: Tetrahedron Letters, Vol. 32, No. 35, 1991, p. 4525-4528.

Research output: Contribution to journalArticle

Chida, Noritaka ; Ohtsuka, Masami ; Ogawa, Seiichiro. / Stereoselective total synthesis of (+)-lycoricidine. In: Tetrahedron Letters. 1991 ; Vol. 32, No. 35. pp. 4525-4528.
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