Abstract
Highly substituted 2-cyclopentenones were stereospecifically and regioselectively constructed with high catalytic efficiency through Lewis-acid catalyzed decarboxylative Nazarov cyclization of the cyclic carbonate derivative, which is prepared by reacting the propargyl alcohol with carbon dioxide in the presence of a silver catalyst. The stereochemistry of the 2-cyclopentenone is strictly controlled by the geometry of the alkene in the starting material. This method is applicable for various substrates.
Original language | English |
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Pages (from-to) | 11594-11598 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 56 |
Issue number | 38 |
DOIs | |
Publication status | Published - 2017 Sept 11 |
Keywords
- C−C bond formation
- carbon dioxide
- electrocyclic reactions
- silver
- stereospecific reactions
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)