Strategies to prevent pancreatic fistula after pancreaticoduodenectomy

Yasuhiro Ito, Takeshi Kenmochi, Tomoyuki Irino, Tomohisa Egawa, Shinobu Hayashi, Atsushi Nagashima, Yuukou Kitagawa

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background/Aims: We evaluated the prevention of pancreatic fistula after pancreaticoduodenectomy in a retrospective clinical study. Methodology: Eighty patients undergoing pancreaticoduodenectomy between April 2007 and August 2011 were recruited. In all patients, the pancreas was reconstructed first, followed by reconstruction of the hepatic duct and the duodenum or stomach. Results: Pancreatic fistulae were observed in 21 of 80 patients (26.3%; Grade A/B/C: 9/12/0). The incidence of pancreatic fistula in patients with soft pancreas was higher than that in patients with hard pancreas (p<0.01). We investigated 54 patients with soft pancreas and pancreatic fistulae were diagnosed in 19 patients (35.2%; Grade A/B/C: 8/11/0). We evaluated pancreatic drainage methods (internal stent/external stent: 20/34) and in patients with soft pancreata, pancreatic fistulae were observed in 11 patients (55%) with internal stents vs. eight patients (23.5%) with external stents (p<0.05). Conclusions: We evaluated the management of pancreatic drainage methods and external stents were associated with a significantly lower incidence of pancreatic fistula compared with internal stents. We expect that external drainage of soft pancreas will decrease pancreatic juice leakage into the abdominal cavity. Many randomised control trials on pancreatic drainage have been reported recently; we plan to study them.

Original languageEnglish
Pages (from-to)2609-2613
Number of pages5
JournalHepato-Gastroenterology
Volume59
Issue number120
DOIs
Publication statusPublished - 2012 Nov

Fingerprint

Pancreatic Fistula
Pancreaticoduodenectomy
Stents
Pancreas
Drainage
Common Hepatic Duct
Pancreatic Juice
Abdominal Cavity
Incidence
Duodenum
Stomach
Retrospective Studies

Keywords

  • Pancreatic fistula
  • Pancreatic stent
  • Pancreaticoduodenectomy

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

Cite this

Strategies to prevent pancreatic fistula after pancreaticoduodenectomy. / Ito, Yasuhiro; Kenmochi, Takeshi; Irino, Tomoyuki; Egawa, Tomohisa; Hayashi, Shinobu; Nagashima, Atsushi; Kitagawa, Yuukou.

In: Hepato-Gastroenterology, Vol. 59, No. 120, 11.2012, p. 2609-2613.

Research output: Contribution to journalArticle

Ito, Y, Kenmochi, T, Irino, T, Egawa, T, Hayashi, S, Nagashima, A & Kitagawa, Y 2012, 'Strategies to prevent pancreatic fistula after pancreaticoduodenectomy', Hepato-Gastroenterology, vol. 59, no. 120, pp. 2609-2613. https://doi.org/10.5754/hge12171
Ito Y, Kenmochi T, Irino T, Egawa T, Hayashi S, Nagashima A et al. Strategies to prevent pancreatic fistula after pancreaticoduodenectomy. Hepato-Gastroenterology. 2012 Nov;59(120):2609-2613. https://doi.org/10.5754/hge12171
Ito, Yasuhiro ; Kenmochi, Takeshi ; Irino, Tomoyuki ; Egawa, Tomohisa ; Hayashi, Shinobu ; Nagashima, Atsushi ; Kitagawa, Yuukou. / Strategies to prevent pancreatic fistula after pancreaticoduodenectomy. In: Hepato-Gastroenterology. 2012 ; Vol. 59, No. 120. pp. 2609-2613.
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