@inproceedings{fff50e0e3d7948b4a5371283b5bf1f65,
title = "Stretching motion-driven ECM-based pulsatile flow generator for mimicking venous blood flow in vivo",
abstract = "We present a pulsatile flow generator with an extracellular matrix (ECM)-based microfluidic device for mimicking venous blood flow in vivo. The pulsatile flow can be generated by directly stretching the ECM channel with stepping motors, imitating in vivo veins compressed by surrounding muscles. The flow velocity was estimated by the theoretical calculation based on finite element simulation. Moreover, vein endothelial cells were cultured in our device with fluidic shear stress and stretch stress simultaneously.",
keywords = "Collagen, Mechanical stress, Microfluidics, Pulsatile flow, Tissue engineering",
author = "Azusa Shimizu and Goh, {Wei Huang} and Shun Itai and Michinao Hashimoto and Sigenori Miura and Hiroaki Onoe",
note = "Funding Information: This work was partly supported by Grant-in Aid for Scientific Research (B) (19H04440) from Japan Society for the Promotion of Science (JSPS), Japan, and the research grant from Digital Manufacturing and Design Centre (DManD) at Singapore University of Technology and Design (SUTD) (RGDM1620503). Publisher Copyright: {\textcopyright} 2019 CBMS-0001.; 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 ; Conference date: 27-10-2019 Through 31-10-2019",
year = "2019",
language = "English",
series = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019",
publisher = "Chemical and Biological Microsystems Society",
pages = "314--315",
booktitle = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019",
}