Structural and conformational studies on euphohelioscopins A and B and related diterpenes

Yoshikazu Shizuri, Seiji Kosemura, Jiro Ohtsuka, Yukimasa Terada, Shosuke Yamamura

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Two new toxic diterpenes (euphohelioscopins A and B) and two euphoscopin-type ones (euphoscopins C and D) have been isolated from the plant Euphorbia helioscopia L., and their stereostructures and conformations also been elucidated on the basis of their spectral data and some chemical evidence, together with successful application of molecular mechanics calculations to such flexible molecules as described herein.

Original languageEnglish
Pages (from-to)2577-2580
Number of pages4
JournalTetrahedron Letters
Volume24
Issue number25
DOIs
Publication statusPublished - 1983

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Euphorbia
Molecular mechanics
Diterpenes
Poisons
Mechanics
Conformations
Molecules
euphohelioscopin A

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Structural and conformational studies on euphohelioscopins A and B and related diterpenes. / Shizuri, Yoshikazu; Kosemura, Seiji; Ohtsuka, Jiro; Terada, Yukimasa; Yamamura, Shosuke.

In: Tetrahedron Letters, Vol. 24, No. 25, 1983, p. 2577-2580.

Research output: Contribution to journalArticle

Shizuri, Yoshikazu ; Kosemura, Seiji ; Ohtsuka, Jiro ; Terada, Yukimasa ; Yamamura, Shosuke. / Structural and conformational studies on euphohelioscopins A and B and related diterpenes. In: Tetrahedron Letters. 1983 ; Vol. 24, No. 25. pp. 2577-2580.
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