Structural and conformational studies on euphornin and related diterpenes

Yoshikazu Shizuri, Seiji Kosemura, Jiro Ohtsuka, Yukimasa Terada, Shosuke Yamamura, Shigeru Ohba, Masatoki Ito, Yoshihiko Saito

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23 Citations (Scopus)

Abstract

In addition to euphornin, three new toxic substances (euphornins A, B and C) have been isolated from the plant Euphorbia helioscopia L., and their absolute stereostructures also been elucidated on the basis of their spectral data and some chemical evidence together with an X-ray crystallographic analysis of the p-bromobenzoate derived from euphornin. Furthermore, their conformations have also been discussed.

Original languageEnglish
Pages (from-to)1155-1158
Number of pages4
JournalTetrahedron Letters
Volume25
Issue number11
DOIs
Publication statusPublished - 1984

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ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Shizuri, Y., Kosemura, S., Ohtsuka, J., Terada, Y., Yamamura, S., Ohba, S., Ito, M., & Saito, Y. (1984). Structural and conformational studies on euphornin and related diterpenes. Tetrahedron Letters, 25(11), 1155-1158. https://doi.org/10.1016/S0040-4039(01)91548-5