Structural Features of Ukonan C, a Reticuloendothelial System-Activating Polysaccharide from the Rhizome of Curcuma longa

Ryoko Gonda, Masashi Tomoda

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

The structural features of ukonan C, the polysaccharide having remarkable reticuloendothelial system-potentiating activity obtained from the rhizome of Curcuma longa L., were investigated by methylation analysis, carbon-13 nuclear magnetic resonance, periodate oxidation and enzymic degradation studies. It is mainly made up of arabino-3,6-galactan type and 4,6-branched glucan type structural units. Degradation with a-amylase followed by the elimination of 1,4-linked glucan side chains resulted in a marked decrease of its immunological activity.

Original languageEnglish
Pages (from-to)441-444
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume39
Issue number2
DOIs
Publication statusPublished - 1991

Keywords

  • Curcuma longa
  • enzymic degradation
  • immunological activity
  • methylation analysis
  • polysaccharide structure
  • reticuloendothelial system
  • rhizome
  • ukonan C

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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