Structures and functions of the gut microbial lipidome

Satoshi Morozumi, Masahiro Ueda, Nobuyuki Okahashi, Makoto Arita

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Microbial lipids provide signals that are responsible for maintaining host health and controlling disease. The differences in the structures of microbial lipids have been shown to alter receptor selectivity and agonist/antagonist activity. Advanced lipidomics is an emerging field that helps to elucidate the complex bacterial lipid diversity. The use of cutting-edge technologies is expected to lead to the discovery of new functional metabolites involved in host homeostasis. This review aims to describe recent updates on functional lipid metabolites derived from gut microbiota, their structure-activity relationships, and advanced lipidomics technologies.

Original languageEnglish
Article number159110
JournalBiochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
Volume1867
Issue number3
DOIs
Publication statusPublished - 2022 Mar

Keywords

  • Bioactive lipids
  • Lipidomics
  • Microbiome

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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