Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from an actinomycete

Kiyotake Suenaga, S. Kokubo, C. Shinohara, T. Tsuji, D. Uemura

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Two new lipopeptides, amamistatins A (1) and B, were isolated from an actinomycete. The absolute stereostructure of 1 was determined by spectroscopic and chemical analyses. Amamistatins A (1) and B showed growth inhibition for human tumor cell lines.

Original languageEnglish
Pages (from-to)1945-1948
Number of pages4
JournalTetrahedron Letters
Volume40
Issue number10
DOIs
Publication statusPublished - 1999 Mar 5
Externally publishedYes

Fingerprint

Growth Inhibitors
Actinobacteria
Tumor Cell Line
Tumors
Cells
Lipopeptides
Growth
amamistatin B
amamistatin A

Keywords

  • Degradation
  • Oxazoles
  • Peptides
  • Stereochemistry

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from an actinomycete. / Suenaga, Kiyotake; Kokubo, S.; Shinohara, C.; Tsuji, T.; Uemura, D.

In: Tetrahedron Letters, Vol. 40, No. 10, 05.03.1999, p. 1945-1948.

Research output: Contribution to journalArticle

Suenaga, Kiyotake ; Kokubo, S. ; Shinohara, C. ; Tsuji, T. ; Uemura, D. / Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from an actinomycete. In: Tetrahedron Letters. 1999 ; Vol. 40, No. 10. pp. 1945-1948.
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