Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from an actinomycete

K. Suenaga, S. Kokubo, C. Shinohara, T. Tsuji, D. Uemura

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Two new lipopeptides, amamistatins A (1) and B, were isolated from an actinomycete. The absolute stereostructure of 1 was determined by spectroscopic and chemical analyses. Amamistatins A (1) and B showed growth inhibition for human tumor cell lines.

Original languageEnglish
Pages (from-to)1945-1948
Number of pages4
JournalTetrahedron Letters
Volume40
Issue number10
DOIs
Publication statusPublished - 1999 Mar 5
Externally publishedYes

Keywords

  • Degradation
  • Oxazoles
  • Peptides
  • Stereochemistry

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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