Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from Nocardia asteroides

S. Kokubo, Kiyotake Suenaga, C. Shinohara, T. Tsuji, D. Uemura

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Two new lipopeptides, amamistatins A and B, were isolated from Nocardia asteroides SCRC-A2359, and their absolute stereostructures were determined by spectroscopic and chemical analyses. Amamistatin A inhibited the growth of human rumor cell lines. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)6435-6440
Number of pages6
JournalTetrahedron
Volume56
Issue number35
Publication statusPublished - 2000 Aug 25
Externally publishedYes

Fingerprint

Nocardia asteroides
Growth Inhibitors
Tumor Cell Line
Tumors
Cells
Lipopeptides
Cell Line
Growth
amamistatin A
amamistatin B

Keywords

  • Degradation
  • Oxazoles
  • Peptides
  • Stereochemistry

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from Nocardia asteroides. / Kokubo, S.; Suenaga, Kiyotake; Shinohara, C.; Tsuji, T.; Uemura, D.

In: Tetrahedron, Vol. 56, No. 35, 25.08.2000, p. 6435-6440.

Research output: Contribution to journalArticle

Kokubo, S, Suenaga, K, Shinohara, C, Tsuji, T & Uemura, D 2000, 'Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from Nocardia asteroides', Tetrahedron, vol. 56, no. 35, pp. 6435-6440.
Kokubo, S. ; Suenaga, Kiyotake ; Shinohara, C. ; Tsuji, T. ; Uemura, D. / Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from Nocardia asteroides. In: Tetrahedron. 2000 ; Vol. 56, No. 35. pp. 6435-6440.
@article{9e00cc8dd5fd47b9a665ac641aa1cfa9,
title = "Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from Nocardia asteroides",
abstract = "Two new lipopeptides, amamistatins A and B, were isolated from Nocardia asteroides SCRC-A2359, and their absolute stereostructures were determined by spectroscopic and chemical analyses. Amamistatin A inhibited the growth of human rumor cell lines. (C) 2000 Elsevier Science Ltd.",
keywords = "Degradation, Oxazoles, Peptides, Stereochemistry",
author = "S. Kokubo and Kiyotake Suenaga and C. Shinohara and T. Tsuji and D. Uemura",
year = "2000",
month = "8",
day = "25",
language = "English",
volume = "56",
pages = "6435--6440",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Limited",
number = "35",

}

TY - JOUR

T1 - Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from Nocardia asteroides

AU - Kokubo, S.

AU - Suenaga, Kiyotake

AU - Shinohara, C.

AU - Tsuji, T.

AU - Uemura, D.

PY - 2000/8/25

Y1 - 2000/8/25

N2 - Two new lipopeptides, amamistatins A and B, were isolated from Nocardia asteroides SCRC-A2359, and their absolute stereostructures were determined by spectroscopic and chemical analyses. Amamistatin A inhibited the growth of human rumor cell lines. (C) 2000 Elsevier Science Ltd.

AB - Two new lipopeptides, amamistatins A and B, were isolated from Nocardia asteroides SCRC-A2359, and their absolute stereostructures were determined by spectroscopic and chemical analyses. Amamistatin A inhibited the growth of human rumor cell lines. (C) 2000 Elsevier Science Ltd.

KW - Degradation

KW - Oxazoles

KW - Peptides

KW - Stereochemistry

UR - http://www.scopus.com/inward/record.url?scp=0034714331&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034714331&partnerID=8YFLogxK

M3 - Article

VL - 56

SP - 6435

EP - 6440

JO - Tetrahedron

JF - Tetrahedron

SN - 0040-4020

IS - 35

ER -