Studies on the constituents of Leonotis nepetaefolia

Yuuji Narukawa, N. Shimizu, T. Takeda

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Three new acylated iridoids were isolatad from a methanol extract of Leonotis nepetaefolia R. Br. (Labiatae). Their structures were elucidated as 10-O-(cis-3, 4-dimethoxycinnamoyl) geniposidic acid (2), 10-O-(trans-feruroyl) geniposidic acid (3) and 10-O-(trans-caffeoyl) geniposidic acid (4) on the basis of the spectroscopic data. Antioxidative activities of the compounds were measured by the α, α-diphenyl-β-picrylhydrazyl (DPPH) method. The new iridoid glycoside, 10-O-(trans-caffeoyl) geniposidic acid showed a strong antioxidative activity.

Original languageEnglish
Pages (from-to)79-82
Number of pages4
JournalNatural Medicines
Volume55
Issue number2
Publication statusPublished - 2001

Fingerprint

Lamiaceae
Iridoid Glycosides
Iridoids
Methanol
geniposidic acid

Keywords

  • Antioxidative activity
  • Iridoid glycoside
  • Labiatae
  • Leonotis nepetaefolia

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Narukawa, Y., Shimizu, N., & Takeda, T. (2001). Studies on the constituents of Leonotis nepetaefolia. Natural Medicines, 55(2), 79-82.

Studies on the constituents of Leonotis nepetaefolia. / Narukawa, Yuuji; Shimizu, N.; Takeda, T.

In: Natural Medicines, Vol. 55, No. 2, 2001, p. 79-82.

Research output: Contribution to journalArticle

Narukawa, Y, Shimizu, N & Takeda, T 2001, 'Studies on the constituents of Leonotis nepetaefolia', Natural Medicines, vol. 55, no. 2, pp. 79-82.
Narukawa, Yuuji ; Shimizu, N. ; Takeda, T. / Studies on the constituents of Leonotis nepetaefolia. In: Natural Medicines. 2001 ; Vol. 55, No. 2. pp. 79-82.
@article{337309499d234508ae36173cf6302d14,
title = "Studies on the constituents of Leonotis nepetaefolia",
abstract = "Three new acylated iridoids were isolatad from a methanol extract of Leonotis nepetaefolia R. Br. (Labiatae). Their structures were elucidated as 10-O-(cis-3, 4-dimethoxycinnamoyl) geniposidic acid (2), 10-O-(trans-feruroyl) geniposidic acid (3) and 10-O-(trans-caffeoyl) geniposidic acid (4) on the basis of the spectroscopic data. Antioxidative activities of the compounds were measured by the α, α-diphenyl-β-picrylhydrazyl (DPPH) method. The new iridoid glycoside, 10-O-(trans-caffeoyl) geniposidic acid showed a strong antioxidative activity.",
keywords = "Antioxidative activity, Iridoid glycoside, Labiatae, Leonotis nepetaefolia",
author = "Yuuji Narukawa and N. Shimizu and T. Takeda",
year = "2001",
language = "English",
volume = "55",
pages = "79--82",
journal = "Journal of Natural Medicines",
issn = "1861-0293",
publisher = "Springer Japan",
number = "2",

}

TY - JOUR

T1 - Studies on the constituents of Leonotis nepetaefolia

AU - Narukawa, Yuuji

AU - Shimizu, N.

AU - Takeda, T.

PY - 2001

Y1 - 2001

N2 - Three new acylated iridoids were isolatad from a methanol extract of Leonotis nepetaefolia R. Br. (Labiatae). Their structures were elucidated as 10-O-(cis-3, 4-dimethoxycinnamoyl) geniposidic acid (2), 10-O-(trans-feruroyl) geniposidic acid (3) and 10-O-(trans-caffeoyl) geniposidic acid (4) on the basis of the spectroscopic data. Antioxidative activities of the compounds were measured by the α, α-diphenyl-β-picrylhydrazyl (DPPH) method. The new iridoid glycoside, 10-O-(trans-caffeoyl) geniposidic acid showed a strong antioxidative activity.

AB - Three new acylated iridoids were isolatad from a methanol extract of Leonotis nepetaefolia R. Br. (Labiatae). Their structures were elucidated as 10-O-(cis-3, 4-dimethoxycinnamoyl) geniposidic acid (2), 10-O-(trans-feruroyl) geniposidic acid (3) and 10-O-(trans-caffeoyl) geniposidic acid (4) on the basis of the spectroscopic data. Antioxidative activities of the compounds were measured by the α, α-diphenyl-β-picrylhydrazyl (DPPH) method. The new iridoid glycoside, 10-O-(trans-caffeoyl) geniposidic acid showed a strong antioxidative activity.

KW - Antioxidative activity

KW - Iridoid glycoside

KW - Labiatae

KW - Leonotis nepetaefolia

UR - http://www.scopus.com/inward/record.url?scp=0034995792&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034995792&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0034995792

VL - 55

SP - 79

EP - 82

JO - Journal of Natural Medicines

JF - Journal of Natural Medicines

SN - 1861-0293

IS - 2

ER -