Studies on the constituents of Leonotis nepetaefolia

Y. Narukawa; N. Shimizu; T. Takeda

Studies on the constituents of Leonotis nepetaefolia

Y. Narukawa, N. Shimizu, T. Takeda

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Three new acylated iridoids were isolatad from a methanol extract of Leonotis nepetaefolia R. Br. (Labiatae). Their structures were elucidated as 10-O-(cis-3, 4-dimethoxycinnamoyl) geniposidic acid (2), 10-O-(trans-feruroyl) geniposidic acid (3) and 10-O-(trans-caffeoyl) geniposidic acid (4) on the basis of the spectroscopic data. Antioxidative activities of the compounds were measured by the α, α-diphenyl-β-picrylhydrazyl (DPPH) method. The new iridoid glycoside, 10-O-(trans-caffeoyl) geniposidic acid showed a strong antioxidative activity.

Original language	English
Pages (from-to)	79-82
Number of pages	4
Journal	Natural Medicines
Volume	55
Issue number	2
Publication status	Published - 2001 Jan 1

Keywords

Antioxidative activity
Iridoid glycoside
Labiatae
Leonotis nepetaefolia

ASJC Scopus subject areas

Molecular Medicine

Cite this

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abstract = "Three new acylated iridoids were isolatad from a methanol extract of Leonotis nepetaefolia R. Br. (Labiatae). Their structures were elucidated as 10-O-(cis-3, 4-dimethoxycinnamoyl) geniposidic acid (2), 10-O-(trans-feruroyl) geniposidic acid (3) and 10-O-(trans-caffeoyl) geniposidic acid (4) on the basis of the spectroscopic data. Antioxidative activities of the compounds were measured by the α, α-diphenyl-β-picrylhydrazyl (DPPH) method. The new iridoid glycoside, 10-O-(trans-caffeoyl) geniposidic acid showed a strong antioxidative activity.",

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AU - Shimizu, N.

AU - Takeda, T.

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N2 - Three new acylated iridoids were isolatad from a methanol extract of Leonotis nepetaefolia R. Br. (Labiatae). Their structures were elucidated as 10-O-(cis-3, 4-dimethoxycinnamoyl) geniposidic acid (2), 10-O-(trans-feruroyl) geniposidic acid (3) and 10-O-(trans-caffeoyl) geniposidic acid (4) on the basis of the spectroscopic data. Antioxidative activities of the compounds were measured by the α, α-diphenyl-β-picrylhydrazyl (DPPH) method. The new iridoid glycoside, 10-O-(trans-caffeoyl) geniposidic acid showed a strong antioxidative activity.

AB - Three new acylated iridoids were isolatad from a methanol extract of Leonotis nepetaefolia R. Br. (Labiatae). Their structures were elucidated as 10-O-(cis-3, 4-dimethoxycinnamoyl) geniposidic acid (2), 10-O-(trans-feruroyl) geniposidic acid (3) and 10-O-(trans-caffeoyl) geniposidic acid (4) on the basis of the spectroscopic data. Antioxidative activities of the compounds were measured by the α, α-diphenyl-β-picrylhydrazyl (DPPH) method. The new iridoid glycoside, 10-O-(trans-caffeoyl) geniposidic acid showed a strong antioxidative activity.

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Studies on the constituents of Leonotis nepetaefolia

Abstract

Keywords

ASJC Scopus subject areas

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