Abstract
Background. The Japan Thyroid Association recently published guidelines for clinical practice for the management of thyroid nodules, which include a diagnostic system for reporting thyroid fine needle aspiration cytology. It is characterized by the subclassification of follicular neoplasms, which is different from other internationally accepted reporting systems. Materials and Methods. This study examined observer variability in the subclassification of follicular neoplasms among 4 reviewers using Papanicolaou-stained smear samples from 20 surgically treated patients with indeterminate cytology. Results. The favor malignant subcategory had high predictive value of malignancy (risk of malignancy: 60-75%) and good agreement among the 4 reviewers (κ = 0.7714). Conclusion. These results clearly confirmed that the risk stratification of follicular neoplasms, which was adapted from cytology practice of high-volume thyroid centers in Japan, can provide clinically helpful information to estimate the risk of malignancy and to triage patients for surgery.
| Original language | English |
|---|---|
| Article number | 938305 |
| Journal | International Journal of Endocrinology |
| Volume | 2015 |
| DOIs | |
| Publication status | Published - 2015 |
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ASJC Scopus subject areas
- Endocrine and Autonomic Systems
- Endocrinology
- Endocrinology, Diabetes and Metabolism
Cite this
Subclassification of follicular neoplasms recommended by the Japan thyroid association reporting system of thyroid cytology. / Kakudo, Kennichi; Kameyama, Kaori; Hirokawa, Mitsuyoshi; Katoh, Ryohei; Nakamura, Hirotoshi.
In: International Journal of Endocrinology, Vol. 2015, 938305, 2015.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Subclassification of follicular neoplasms recommended by the Japan thyroid association reporting system of thyroid cytology
AU - Kakudo, Kennichi
AU - Kameyama, Kaori
AU - Hirokawa, Mitsuyoshi
AU - Katoh, Ryohei
AU - Nakamura, Hirotoshi
PY - 2015
Y1 - 2015
N2 - Background. The Japan Thyroid Association recently published guidelines for clinical practice for the management of thyroid nodules, which include a diagnostic system for reporting thyroid fine needle aspiration cytology. It is characterized by the subclassification of follicular neoplasms, which is different from other internationally accepted reporting systems. Materials and Methods. This study examined observer variability in the subclassification of follicular neoplasms among 4 reviewers using Papanicolaou-stained smear samples from 20 surgically treated patients with indeterminate cytology. Results. The favor malignant subcategory had high predictive value of malignancy (risk of malignancy: 60-75%) and good agreement among the 4 reviewers (κ = 0.7714). Conclusion. These results clearly confirmed that the risk stratification of follicular neoplasms, which was adapted from cytology practice of high-volume thyroid centers in Japan, can provide clinically helpful information to estimate the risk of malignancy and to triage patients for surgery.
AB - Background. The Japan Thyroid Association recently published guidelines for clinical practice for the management of thyroid nodules, which include a diagnostic system for reporting thyroid fine needle aspiration cytology. It is characterized by the subclassification of follicular neoplasms, which is different from other internationally accepted reporting systems. Materials and Methods. This study examined observer variability in the subclassification of follicular neoplasms among 4 reviewers using Papanicolaou-stained smear samples from 20 surgically treated patients with indeterminate cytology. Results. The favor malignant subcategory had high predictive value of malignancy (risk of malignancy: 60-75%) and good agreement among the 4 reviewers (κ = 0.7714). Conclusion. These results clearly confirmed that the risk stratification of follicular neoplasms, which was adapted from cytology practice of high-volume thyroid centers in Japan, can provide clinically helpful information to estimate the risk of malignancy and to triage patients for surgery.
UR - http://www.scopus.com/inward/record.url?scp=84924089475&partnerID=8YFLogxK
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U2 - 10.1155/2015/938305
DO - 10.1155/2015/938305
M3 - Article
VL - 2015
JO - International Journal of Endocrinology
JF - International Journal of Endocrinology
SN - 1687-8337
M1 - 938305
ER -