Abstract
Argon plasma coagulation (APC) is considered to be a safe thermocoagulation technique, but some reports show perforation and deformity during and after APC. In this study, we investigated the usefulness of prior submucosal injection for APC. APC over the mucosa was performed on fresh resected porcine esophagus, stomach, and colon with prior submucosal injection of normal saline (injection group) and without it (control group). The depth of tissue damage increased linearly with pulse duration up to the shallower submucosal layer in both groups. After that, tissue damage in the injection group remained confined to the shallower submucosal layer under any condition, whereas that in the control group continued to extend. The tissue damages of the injection groups were significantly (P < 0.05) shallower than those of the control groups that reached the deeper submucosal layer in all the organs. Submucosal injection of normal saline before the application of APC may limit tissue damage and prevent perforation and deformity.
| Original language | English |
|---|---|
| Pages (from-to) | 307-311 |
| Number of pages | 5 |
| Journal | Surgical Laparoscopy, Endoscopy and Percutaneous Techniques |
| Volume | 16 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2006 Oct |
| Externally published | Yes |
Fingerprint
Keywords
- Argon plasma coagulation
- Depth control
- Endoscopic application
- Normal saline
- Submucosal injection
- The gastrointestinal tract
ASJC Scopus subject areas
- Surgery
Cite this
Submucosal injection of normal saline may prevent tissue damage from argon plasma coagulation : An experimental study using resected porcine esophagus, stomach, and colon. / Fujishiro, Mitsuhiro; Yahagi, Naohisa; Nakamura, Masanori; Kakushima, Naomi; Kodashima, Shinya; Ono, Satoshi; Kobayashi, Katsuya; Hashimoto, Takuhei; Yamamichi, Nobutake; Tateishi, Ayako; Shimizu, Yasuhito; Oka, Masashi; Ichinose, Masao; Omata, Masao.
In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques, Vol. 16, No. 5, 10.2006, p. 307-311.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Submucosal injection of normal saline may prevent tissue damage from argon plasma coagulation
T2 - An experimental study using resected porcine esophagus, stomach, and colon
AU - Fujishiro, Mitsuhiro
AU - Yahagi, Naohisa
AU - Nakamura, Masanori
AU - Kakushima, Naomi
AU - Kodashima, Shinya
AU - Ono, Satoshi
AU - Kobayashi, Katsuya
AU - Hashimoto, Takuhei
AU - Yamamichi, Nobutake
AU - Tateishi, Ayako
AU - Shimizu, Yasuhito
AU - Oka, Masashi
AU - Ichinose, Masao
AU - Omata, Masao
PY - 2006/10
Y1 - 2006/10
N2 - Argon plasma coagulation (APC) is considered to be a safe thermocoagulation technique, but some reports show perforation and deformity during and after APC. In this study, we investigated the usefulness of prior submucosal injection for APC. APC over the mucosa was performed on fresh resected porcine esophagus, stomach, and colon with prior submucosal injection of normal saline (injection group) and without it (control group). The depth of tissue damage increased linearly with pulse duration up to the shallower submucosal layer in both groups. After that, tissue damage in the injection group remained confined to the shallower submucosal layer under any condition, whereas that in the control group continued to extend. The tissue damages of the injection groups were significantly (P < 0.05) shallower than those of the control groups that reached the deeper submucosal layer in all the organs. Submucosal injection of normal saline before the application of APC may limit tissue damage and prevent perforation and deformity.
AB - Argon plasma coagulation (APC) is considered to be a safe thermocoagulation technique, but some reports show perforation and deformity during and after APC. In this study, we investigated the usefulness of prior submucosal injection for APC. APC over the mucosa was performed on fresh resected porcine esophagus, stomach, and colon with prior submucosal injection of normal saline (injection group) and without it (control group). The depth of tissue damage increased linearly with pulse duration up to the shallower submucosal layer in both groups. After that, tissue damage in the injection group remained confined to the shallower submucosal layer under any condition, whereas that in the control group continued to extend. The tissue damages of the injection groups were significantly (P < 0.05) shallower than those of the control groups that reached the deeper submucosal layer in all the organs. Submucosal injection of normal saline before the application of APC may limit tissue damage and prevent perforation and deformity.
KW - Argon plasma coagulation
KW - Depth control
KW - Endoscopic application
KW - Normal saline
KW - Submucosal injection
KW - The gastrointestinal tract
UR - http://www.scopus.com/inward/record.url?scp=33750344070&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33750344070&partnerID=8YFLogxK
U2 - 10.1097/01.sle.0000213739.85277.3d
DO - 10.1097/01.sle.0000213739.85277.3d
M3 - Article
C2 - 17057569
AN - SCOPUS:33750344070
VL - 16
SP - 307
EP - 311
JO - Surgical Laparoscopy, Endoscopy and Percutaneous Techniques
JF - Surgical Laparoscopy, Endoscopy and Percutaneous Techniques
SN - 1530-4515
IS - 5
ER -