Successful function-preserving therapy for chondroblastoma of the temporal bone involving the temporomandibular joint

Junkichi Yokoyama, Hitoshi Yoshimoto, Shin Ito, Shinichi Ohba, Mitsuhisa Fujimaki, Katsuhisa Ikeda, Masaki Yazawa, Nozomi Fujimiya, Makoto Hanaguri

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We present a case involving a late diagnosis of chondroblastoma of the temporal skull base involving the temporomandibular joint (TMJ). Following an initial misdiagnosis and unsuccessful treatment over a period of 5 years, the patient was referred to our department for further evaluation and possible surgical intervention for occlusal abnormalities, trismus, clicking of the TMJ, and hearing impairment. Based on preoperative immunochemical studies showing positive reaction of multinucleated giant cells for S-100 protein, the final diagnosis was chondroblastoma. The surgical approach - postauricular incision and total parotidectomy, with complete removal of the temporal bone, including the TMJ via the extended middle fossa - was successful in preserving facial nerves and diminishing clinical manifestations. This study highlights a misdiagnosed case in an effort to underline the importance of medical examinations and accurate differential diagnosis in cases involving any tumor mass in the temporal bone.

Original languageEnglish
Pages (from-to)74-81
Number of pages8
JournalCase Reports in Oncology
Volume4
Issue number1
DOIs
Publication statusPublished - 2011 Jan

Fingerprint

Chondroblastoma
Temporal Bone
Temporomandibular Joint
Diagnostic Errors
Trismus
S100 Proteins
Delayed Diagnosis
Skull Base
Facial Nerve
Giant Cells
Hearing Loss
Differential Diagnosis
Therapeutics
Neoplasms

Keywords

  • Chondroblastoma
  • Parotidectomy
  • Temporal bone
  • Temporomandibular joint
  • Trismus

ASJC Scopus subject areas

  • Oncology

Cite this

Successful function-preserving therapy for chondroblastoma of the temporal bone involving the temporomandibular joint. / Yokoyama, Junkichi; Yoshimoto, Hitoshi; Ito, Shin; Ohba, Shinichi; Fujimaki, Mitsuhisa; Ikeda, Katsuhisa; Yazawa, Masaki; Fujimiya, Nozomi; Hanaguri, Makoto.

In: Case Reports in Oncology, Vol. 4, No. 1, 01.2011, p. 74-81.

Research output: Contribution to journalArticle

Yokoyama, J, Yoshimoto, H, Ito, S, Ohba, S, Fujimaki, M, Ikeda, K, Yazawa, M, Fujimiya, N & Hanaguri, M 2011, 'Successful function-preserving therapy for chondroblastoma of the temporal bone involving the temporomandibular joint', Case Reports in Oncology, vol. 4, no. 1, pp. 74-81. https://doi.org/10.1159/000324640
Yokoyama, Junkichi ; Yoshimoto, Hitoshi ; Ito, Shin ; Ohba, Shinichi ; Fujimaki, Mitsuhisa ; Ikeda, Katsuhisa ; Yazawa, Masaki ; Fujimiya, Nozomi ; Hanaguri, Makoto. / Successful function-preserving therapy for chondroblastoma of the temporal bone involving the temporomandibular joint. In: Case Reports in Oncology. 2011 ; Vol. 4, No. 1. pp. 74-81.
@article{94e823bda6af4e6f9dd0ce28785eb60b,
title = "Successful function-preserving therapy for chondroblastoma of the temporal bone involving the temporomandibular joint",
abstract = "We present a case involving a late diagnosis of chondroblastoma of the temporal skull base involving the temporomandibular joint (TMJ). Following an initial misdiagnosis and unsuccessful treatment over a period of 5 years, the patient was referred to our department for further evaluation and possible surgical intervention for occlusal abnormalities, trismus, clicking of the TMJ, and hearing impairment. Based on preoperative immunochemical studies showing positive reaction of multinucleated giant cells for S-100 protein, the final diagnosis was chondroblastoma. The surgical approach - postauricular incision and total parotidectomy, with complete removal of the temporal bone, including the TMJ via the extended middle fossa - was successful in preserving facial nerves and diminishing clinical manifestations. This study highlights a misdiagnosed case in an effort to underline the importance of medical examinations and accurate differential diagnosis in cases involving any tumor mass in the temporal bone.",
keywords = "Chondroblastoma, Parotidectomy, Temporal bone, Temporomandibular joint, Trismus",
author = "Junkichi Yokoyama and Hitoshi Yoshimoto and Shin Ito and Shinichi Ohba and Mitsuhisa Fujimaki and Katsuhisa Ikeda and Masaki Yazawa and Nozomi Fujimiya and Makoto Hanaguri",
year = "2011",
month = "1",
doi = "10.1159/000324640",
language = "English",
volume = "4",
pages = "74--81",
journal = "Case Reports in Oncology",
issn = "1662-6575",
number = "1",

}

TY - JOUR

T1 - Successful function-preserving therapy for chondroblastoma of the temporal bone involving the temporomandibular joint

AU - Yokoyama, Junkichi

AU - Yoshimoto, Hitoshi

AU - Ito, Shin

AU - Ohba, Shinichi

AU - Fujimaki, Mitsuhisa

AU - Ikeda, Katsuhisa

AU - Yazawa, Masaki

AU - Fujimiya, Nozomi

AU - Hanaguri, Makoto

PY - 2011/1

Y1 - 2011/1

N2 - We present a case involving a late diagnosis of chondroblastoma of the temporal skull base involving the temporomandibular joint (TMJ). Following an initial misdiagnosis and unsuccessful treatment over a period of 5 years, the patient was referred to our department for further evaluation and possible surgical intervention for occlusal abnormalities, trismus, clicking of the TMJ, and hearing impairment. Based on preoperative immunochemical studies showing positive reaction of multinucleated giant cells for S-100 protein, the final diagnosis was chondroblastoma. The surgical approach - postauricular incision and total parotidectomy, with complete removal of the temporal bone, including the TMJ via the extended middle fossa - was successful in preserving facial nerves and diminishing clinical manifestations. This study highlights a misdiagnosed case in an effort to underline the importance of medical examinations and accurate differential diagnosis in cases involving any tumor mass in the temporal bone.

AB - We present a case involving a late diagnosis of chondroblastoma of the temporal skull base involving the temporomandibular joint (TMJ). Following an initial misdiagnosis and unsuccessful treatment over a period of 5 years, the patient was referred to our department for further evaluation and possible surgical intervention for occlusal abnormalities, trismus, clicking of the TMJ, and hearing impairment. Based on preoperative immunochemical studies showing positive reaction of multinucleated giant cells for S-100 protein, the final diagnosis was chondroblastoma. The surgical approach - postauricular incision and total parotidectomy, with complete removal of the temporal bone, including the TMJ via the extended middle fossa - was successful in preserving facial nerves and diminishing clinical manifestations. This study highlights a misdiagnosed case in an effort to underline the importance of medical examinations and accurate differential diagnosis in cases involving any tumor mass in the temporal bone.

KW - Chondroblastoma

KW - Parotidectomy

KW - Temporal bone

KW - Temporomandibular joint

KW - Trismus

UR - http://www.scopus.com/inward/record.url?scp=79957589844&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79957589844&partnerID=8YFLogxK

U2 - 10.1159/000324640

DO - 10.1159/000324640

M3 - Article

C2 - 21475594

AN - SCOPUS:79957589844

VL - 4

SP - 74

EP - 81

JO - Case Reports in Oncology

JF - Case Reports in Oncology

SN - 1662-6575

IS - 1

ER -