Successful management of metastatic urothelial carcinoma with gemcitabine and paclitaxel chemotherapy in a hemodialysis patient

Hiroki Ide, Atsuko Satou, Katsura Hoshino, Yota Yasumizu, Yasumitsu Uchida, Yuji Tasaka, Takeshi Masuda

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

This is the first report of urothelial carcinoma (UC) in a hemodialysis (HD) patient treated with almost the same doses of gemcitabine and paclitaxel (GP) as those administered to patients with normal renal function. There have been some reports of UC treated with cisplatin-based chemotherapy in HD patients. However, there have only been a few reports of UC treated with GP in HD patients. Furthermore, to our knowledge, there has not been any report of UC in a HD patient treated with almost the same doses of GP as those in patients with normal renal function. Following cystectomy for bladder cancer, a 73-year-old woman undergoing HD developed lung metastasis and received combination chemotherapy with almost the same doses of GP as those in patients with normal renal function. After three cycles were completed, metastatic tumors disappeared and there has not been any recurrence or metastasis for 1 year to date. Furthermore, there were no grade 3 or 4 adverse effects during this treatment.

Original languageEnglish
Pages (from-to)245-247
Number of pages3
JournalUrologia Internationalis
Volume87
Issue number2
DOIs
Publication statusPublished - 2011 Sep 1
Externally publishedYes

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Keywords

  • Chemotherapy
  • Gemcitabine
  • Hemodialysis
  • Paclitaxel
  • Urothelial carcinoma

ASJC Scopus subject areas

  • Urology

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