TY - JOUR
T1 - Successful Pregnancy After Sacrectomy Combined With Chemotherapy and Radiation for Ewing Sarcoma
T2 - Case Report and Literature Review
AU - Kakogawa, Jun
AU - Nako, Takafumi
AU - Kawamura, Kazuhiro
AU - Nakamura, Shin
AU - Mochiduki, Ayako
AU - Kanayama, Naohiro
AU - Tanaka, Mamoru
PY - 2015/6/1
Y1 - 2015/6/1
N2 - Ewing sarcoma is considered to have a poor prognosis. Recent advances in multidisciplinary management have resulted in a marked improvement in long-term survival. Case: We describe a case of successful pregnancy in a patient who underwent sacrectomy combined with multi-agent chemotherapy and radiotherapy for Ewing sarcoma. The patient was diagnosed with Ewing sarcoma of the sacrum at the age of 16. The ovaries were transposed, the uterus was shielded, and a gonadotropin-releasing hormone agonist was used during treatment to protect ovarian function. The patient spontaneously conceived at the age of 27. After an uneventful pregnancy, the patient delivered a healthy neonate at term by cesarean section. Summary and Conclusions: Successful pregnancy and delivery can be achieved after multi-modality treatment with pretreatment intervention for fertility preservation.
AB - Ewing sarcoma is considered to have a poor prognosis. Recent advances in multidisciplinary management have resulted in a marked improvement in long-term survival. Case: We describe a case of successful pregnancy in a patient who underwent sacrectomy combined with multi-agent chemotherapy and radiotherapy for Ewing sarcoma. The patient was diagnosed with Ewing sarcoma of the sacrum at the age of 16. The ovaries were transposed, the uterus was shielded, and a gonadotropin-releasing hormone agonist was used during treatment to protect ovarian function. The patient spontaneously conceived at the age of 27. After an uneventful pregnancy, the patient delivered a healthy neonate at term by cesarean section. Summary and Conclusions: Successful pregnancy and delivery can be achieved after multi-modality treatment with pretreatment intervention for fertility preservation.
KW - Ewing sarcoma
KW - Fertility preservation
KW - Pregnancy
KW - Sacrectomy
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U2 - 10.1016/j.jpag.2014.06.009
DO - 10.1016/j.jpag.2014.06.009
M3 - Article
C2 - 25823720
AN - SCOPUS:84930481263
VL - 28
SP - e79-e81
JO - Journal of Pediatric and Adolescent Gynecology
JF - Journal of Pediatric and Adolescent Gynecology
SN - 1083-3188
IS - 3
ER -