Successful Pregnancy After Sacrectomy Combined With Chemotherapy and Radiation for Ewing Sarcoma: Case Report and Literature Review

Jun Kakogawa; Takafumi Nako; Kazuhiro Kawamura; Shin Nakamura; Ayako Mochiduki; Naohiro Kanayama; Mamoru Tanaka

doi:10.1016/j.jpag.2014.06.009

Successful Pregnancy After Sacrectomy Combined With Chemotherapy and Radiation for Ewing Sarcoma: Case Report and Literature Review

Jun Kakogawa, Takafumi Nako, Kazuhiro Kawamura, Shin Nakamura, Ayako Mochiduki, Naohiro Kanayama, Mamoru Tanaka

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Ewing sarcoma is considered to have a poor prognosis. Recent advances in multidisciplinary management have resulted in a marked improvement in long-term survival. Case: We describe a case of successful pregnancy in a patient who underwent sacrectomy combined with multi-agent chemotherapy and radiotherapy for Ewing sarcoma. The patient was diagnosed with Ewing sarcoma of the sacrum at the age of 16. The ovaries were transposed, the uterus was shielded, and a gonadotropin-releasing hormone agonist was used during treatment to protect ovarian function. The patient spontaneously conceived at the age of 27. After an uneventful pregnancy, the patient delivered a healthy neonate at term by cesarean section. Summary and Conclusions: Successful pregnancy and delivery can be achieved after multi-modality treatment with pretreatment intervention for fertility preservation.

Original language	English
Pages (from-to)	e79-e81
Journal	Journal of Pediatric and Adolescent Gynecology
Volume	28
Issue number	3
DOIs	https://doi.org/10.1016/j.jpag.2014.06.009
Publication status	Published - 2015 Jun 1
Externally published	Yes

Keywords

Ewing sarcoma
Fertility preservation
Pregnancy
Sacrectomy

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynaecology

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10.1016/j.jpag.2014.06.009

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Successful Pregnancy After Sacrectomy Combined With Chemotherapy and Radiation for Ewing Sarcoma : Case Report and Literature Review. / Kakogawa, Jun; Nako, Takafumi; Kawamura, Kazuhiro; Nakamura, Shin; Mochiduki, Ayako; Kanayama, Naohiro; Tanaka, Mamoru.

In: Journal of Pediatric and Adolescent Gynecology, Vol. 28, No. 3, 01.06.2015, p. e79-e81.

Research output: Contribution to journal › Article › peer-review

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abstract = "Ewing sarcoma is considered to have a poor prognosis. Recent advances in multidisciplinary management have resulted in a marked improvement in long-term survival. Case: We describe a case of successful pregnancy in a patient who underwent sacrectomy combined with multi-agent chemotherapy and radiotherapy for Ewing sarcoma. The patient was diagnosed with Ewing sarcoma of the sacrum at the age of 16. The ovaries were transposed, the uterus was shielded, and a gonadotropin-releasing hormone agonist was used during treatment to protect ovarian function. The patient spontaneously conceived at the age of 27. After an uneventful pregnancy, the patient delivered a healthy neonate at term by cesarean section. Summary and Conclusions: Successful pregnancy and delivery can be achieved after multi-modality treatment with pretreatment intervention for fertility preservation.",

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AU - Nakamura, Shin

AU - Mochiduki, Ayako

AU - Kanayama, Naohiro

AU - Tanaka, Mamoru

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AB - Ewing sarcoma is considered to have a poor prognosis. Recent advances in multidisciplinary management have resulted in a marked improvement in long-term survival. Case: We describe a case of successful pregnancy in a patient who underwent sacrectomy combined with multi-agent chemotherapy and radiotherapy for Ewing sarcoma. The patient was diagnosed with Ewing sarcoma of the sacrum at the age of 16. The ovaries were transposed, the uterus was shielded, and a gonadotropin-releasing hormone agonist was used during treatment to protect ovarian function. The patient spontaneously conceived at the age of 27. After an uneventful pregnancy, the patient delivered a healthy neonate at term by cesarean section. Summary and Conclusions: Successful pregnancy and delivery can be achieved after multi-modality treatment with pretreatment intervention for fertility preservation.

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Successful Pregnancy After Sacrectomy Combined With Chemotherapy and Radiation for Ewing Sarcoma: Case Report and Literature Review

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Keywords

ASJC Scopus subject areas

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