Successful Pregnancy After Sacrectomy Combined With Chemotherapy and Radiation for Ewing Sarcoma

Case Report and Literature Review

Jun Kakogawa, Takafumi Nako, Kazuhiro Kawamura, Shin Nakamura, Ayako Mochiduki, Naohiro Kanayama, Mamoru Tanaka

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Ewing sarcoma is considered to have a poor prognosis. Recent advances in multidisciplinary management have resulted in a marked improvement in long-term survival. Case: We describe a case of successful pregnancy in a patient who underwent sacrectomy combined with multi-agent chemotherapy and radiotherapy for Ewing sarcoma. The patient was diagnosed with Ewing sarcoma of the sacrum at the age of 16. The ovaries were transposed, the uterus was shielded, and a gonadotropin-releasing hormone agonist was used during treatment to protect ovarian function. The patient spontaneously conceived at the age of 27. After an uneventful pregnancy, the patient delivered a healthy neonate at term by cesarean section. Summary and Conclusions: Successful pregnancy and delivery can be achieved after multi-modality treatment with pretreatment intervention for fertility preservation.

Original languageEnglish
Pages (from-to)e79-e81
JournalJournal of Pediatric and Adolescent Gynecology
Volume28
Issue number3
DOIs
Publication statusPublished - 2015 Jun 1
Externally publishedYes

Fingerprint

Ewing's Sarcoma
Radiation
Drug Therapy
Pregnancy
Fertility Preservation
Sacrum
Gonadotropin-Releasing Hormone
Cesarean Section
Uterus
Ovary
Radiotherapy
Newborn Infant
Survival
Therapeutics

Keywords

  • Ewing sarcoma
  • Fertility preservation
  • Pregnancy
  • Sacrectomy

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Pediatrics, Perinatology, and Child Health

Cite this

Successful Pregnancy After Sacrectomy Combined With Chemotherapy and Radiation for Ewing Sarcoma : Case Report and Literature Review. / Kakogawa, Jun; Nako, Takafumi; Kawamura, Kazuhiro; Nakamura, Shin; Mochiduki, Ayako; Kanayama, Naohiro; Tanaka, Mamoru.

In: Journal of Pediatric and Adolescent Gynecology, Vol. 28, No. 3, 01.06.2015, p. e79-e81.

Research output: Contribution to journalArticle

Kakogawa, Jun ; Nako, Takafumi ; Kawamura, Kazuhiro ; Nakamura, Shin ; Mochiduki, Ayako ; Kanayama, Naohiro ; Tanaka, Mamoru. / Successful Pregnancy After Sacrectomy Combined With Chemotherapy and Radiation for Ewing Sarcoma : Case Report and Literature Review. In: Journal of Pediatric and Adolescent Gynecology. 2015 ; Vol. 28, No. 3. pp. e79-e81.
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