Successful treatment of adult onset Langerhans cell histiocytosis with multi-drug combination therapy

Eri Matsuki, Yuiko Tsukada, Aya Nakaya, Kenji Yokoyama, Shinichiro Okamoto

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Adult onset Langerhans cell histiocytosis (LCH) is a rare disorder. Its clinical features have been well described in children, however remain poorly defined in adults. Optimal treatment strategy is still under debate. We have encountered two cases of adult onset LCH, which obtained a durable disease control by combination chemotherapy using prednisone, vinblastine and 6-mercaptopurine. Herein, we report their clinical features together with a review of the current literature.

Original languageEnglish
Pages (from-to)909-914
Number of pages6
JournalInternal Medicine
Volume50
Issue number8
DOIs
Publication statusPublished - 2011 May 6

Keywords

  • Adults
  • Combination chemotherapy
  • Langerhans cell histiocytosis

ASJC Scopus subject areas

  • Internal Medicine

Fingerprint Dive into the research topics of 'Successful treatment of adult onset Langerhans cell histiocytosis with multi-drug combination therapy'. Together they form a unique fingerprint.

  • Cite this