Successful treatment of subfoveal choroidal neovascularization associated with combined hamartoma of the retina and retinal pigment epithelium

Makoto Inoue, Koushuke Noda, Susumu Ishida, Takefumi Yamaguchi, Norihiro Nagai, Kei Shinoda, Hajime Shinoda, Yoshihisa Oguchi

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Purpose To describe a patient with subfoveal choroidal neovascularization (CNV) associated with combined hamartoma of the retina and retinal pigment epithelium (CHRRPE), treated successfully by submacular surgery. Design Interventional case report. Methods A 12-year-old girl was referred to our clinic for evaluation. Visual acuity was 20/30 in the affected left eye. Ophthalmoscopy disclosed juxtapapillary CHRRPE and subfoveal pigmented CNV. Vitreous surgery was carried out because of visual deterioration to 20/60. Results The posterior vitreous was strongly attached to glial tissue at the superior margin of the optic disk in the CHRRPE region. The CNV, which was not connected with the CHRRPE, was carefully removed, resulting in visual improvement to 20/20 5 months after surgery. Histologically, the excised membrane showed fibroblast-rich cellular component and a type 2 configuration. Conclusion Submacular surgery can be effective for the treatment of secondary CNV associated with CHRRPE.

Original languageEnglish
Pages (from-to)155-156
Number of pages2
JournalAmerican Journal of Ophthalmology
Volume138
Issue number1
DOIs
Publication statusPublished - 2004 Jul

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Choroidal Neovascularization
Hamartoma
Retinal Pigment Epithelium
Retina
Therapeutics
Ophthalmoscopy
compound A 12
Optic Disk
Neuroglia
Visual Acuity
Fibroblasts
Membranes

ASJC Scopus subject areas

  • Ophthalmology

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Successful treatment of subfoveal choroidal neovascularization associated with combined hamartoma of the retina and retinal pigment epithelium. / Inoue, Makoto; Noda, Koushuke; Ishida, Susumu; Yamaguchi, Takefumi; Nagai, Norihiro; Shinoda, Kei; Shinoda, Hajime; Oguchi, Yoshihisa.

In: American Journal of Ophthalmology, Vol. 138, No. 1, 07.2004, p. 155-156.

Research output: Contribution to journalArticle

Inoue, Makoto ; Noda, Koushuke ; Ishida, Susumu ; Yamaguchi, Takefumi ; Nagai, Norihiro ; Shinoda, Kei ; Shinoda, Hajime ; Oguchi, Yoshihisa. / Successful treatment of subfoveal choroidal neovascularization associated with combined hamartoma of the retina and retinal pigment epithelium. In: American Journal of Ophthalmology. 2004 ; Vol. 138, No. 1. pp. 155-156.
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AU - Inoue, Makoto

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AU - Yamaguchi, Takefumi

AU - Nagai, Norihiro

AU - Shinoda, Kei

AU - Shinoda, Hajime

AU - Oguchi, Yoshihisa

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