Successful treatment with cyclosporin A of pure red cell aplasia associated with rheumatoid arthritis

Takao Fujii; Tomoharu Yajima; Hideto Kameda; Tsuneyo Mimori; Masashi Akizuki; Yasuo Ikeda

Successful treatment with cyclosporin A of pure red cell aplasia associated with rheumatoid arthritis

Takao Fujii, Tomoharu Yajima, Hideto Kameda, Tsuneyo Mimori, Masashi Akizuki, Yasuo Ikeda

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

We describe the first report of a patient with rheumatoid arthritis (RA) who developed refractory pure red cell aplasia that was successfully treated with cyclosporin A (CyA). Since no inhibitory activity against bone marrow was observed in the whole serum, it is possible that the clinical efficacy of CyA on both RA and aplasia was explained by its effects on T cells that might be involved in the development of these diseases.

Original language	English
Pages (from-to)	1803-1805
Number of pages	3
Journal	Journal of Rheumatology
Volume	23
Issue number	10
Publication status	Published - 1996 Oct 24

Keywords

cyclosporin A
pure red cell aplasia
rheumatoid arthritis

ASJC Scopus subject areas

Rheumatology
Immunology and Allergy
Immunology

Cite this

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abstract = "We describe the first report of a patient with rheumatoid arthritis (RA) who developed refractory pure red cell aplasia that was successfully treated with cyclosporin A (CyA). Since no inhibitory activity against bone marrow was observed in the whole serum, it is possible that the clinical efficacy of CyA on both RA and aplasia was explained by its effects on T cells that might be involved in the development of these diseases.",

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AU - Fujii, Takao

AU - Yajima, Tomoharu

AU - Kameda, Hideto

AU - Mimori, Tsuneyo

AU - Akizuki, Masashi

AU - Ikeda, Yasuo

PY - 1996/10/24

Y1 - 1996/10/24

N2 - We describe the first report of a patient with rheumatoid arthritis (RA) who developed refractory pure red cell aplasia that was successfully treated with cyclosporin A (CyA). Since no inhibitory activity against bone marrow was observed in the whole serum, it is possible that the clinical efficacy of CyA on both RA and aplasia was explained by its effects on T cells that might be involved in the development of these diseases.

AB - We describe the first report of a patient with rheumatoid arthritis (RA) who developed refractory pure red cell aplasia that was successfully treated with cyclosporin A (CyA). Since no inhibitory activity against bone marrow was observed in the whole serum, it is possible that the clinical efficacy of CyA on both RA and aplasia was explained by its effects on T cells that might be involved in the development of these diseases.

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ER -

Successful treatment with cyclosporin A of pure red cell aplasia associated with rheumatoid arthritis

Abstract

Keywords

ASJC Scopus subject areas

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