Sunabedine, a novel toxic bromotyrosine-derivative alkaloid from Okinawan sponge, order Verongida

Norihito Maru, Tomoyuki Koyama, Osamu Ohno, Kaoru Yamada, Daisuke Uemura

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Sunabedine (1), a new bromotyrosine-derivative alkaloid, was isolated from the Okinawan sponge, order Verongida. The structure of 1 was determined by spectroscopic analyses. 1 showed the cytotoxicity against B16 mouse melanoma cells and toxicity against brine shrimp.

Original languageEnglish
Pages (from-to)371-375
Number of pages5
JournalHeterocycles
Volume82
Issue number1
DOIs
Publication statusPublished - 2010

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Artemia
Experimental Melanomas
Poisons
Porifera
Cytotoxicity
Alkaloids
Toxicity
Derivatives
bromotyrosine
brine

ASJC Scopus subject areas

  • Analytical Chemistry
  • Organic Chemistry
  • Pharmacology

Cite this

Sunabedine, a novel toxic bromotyrosine-derivative alkaloid from Okinawan sponge, order Verongida. / Maru, Norihito; Koyama, Tomoyuki; Ohno, Osamu; Yamada, Kaoru; Uemura, Daisuke.

In: Heterocycles, Vol. 82, No. 1, 2010, p. 371-375.

Research output: Contribution to journalArticle

Maru, Norihito ; Koyama, Tomoyuki ; Ohno, Osamu ; Yamada, Kaoru ; Uemura, Daisuke. / Sunabedine, a novel toxic bromotyrosine-derivative alkaloid from Okinawan sponge, order Verongida. In: Heterocycles. 2010 ; Vol. 82, No. 1. pp. 371-375.
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