2H nuclear magnetic resonance studies on biosynthesis: Stereochemistry of the 5′-hydrogen atoms of griseofulvin derived from griseophenone B and 4-demethyldehydrogriseofulvin

Yoshihiro Sato, Taiko Oda, Hazime Saitô

Research output: Contribution to journalArticle

10 Citations (Scopus)


2H N.m.r. spectroscopy has been used to establish that in Penicillium urticae, griseofulvin is biosynthesized with the 5′α-configuration of deuterium from [5′-2H] griseophenone B and 4-demethyl-[5′-2H]-dehydrogriseofulvin.

Original languageEnglish
Pages (from-to)135-136
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number3
Publication statusPublished - 1978 Jan 1


ASJC Scopus subject areas

  • Molecular Medicine

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