To investigate the superiority of the Mycobacteria Growth Indicator Tube (MGIT) over Ogawa medium in the detection of acid-fast bacilli (AFB), we surveyed all specimens for AFB culture using Ogawa medium in 1999 and MGIT in 2000. The MGIT method increased the culture-positive rate from 23.1% (Ogawa medium) to 34.5% (p < 0.01). The culture-positive rate in smear-negative specimens was greatly increased (from 9.5% to 16.9%) (p < 0.01). The culture-negative rate in smear-positive specimens was decreased to 19.5% from 27.7% (p < 0.01). More individuals with positive M. tuberculosis cultures were found by the MGIT method than with Ogawa medium. Many more individuals with nontuberculous mycobacteria (NTM), notably those with NTM other than M. avium complex, were detected by the MGIT method than with Ogawa medium. The use of the MGIT method in the clinical laboratory will improve sensitivity in the detection of AFB.
|Number of pages||5|
|Journal||Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society|
|Publication status||Published - 2002 May|
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