Surgical implications of the new IASLC/ ATS/ERS adenocarcinoma classification

P. E. Van Schil, Hisao Asamura, V. W. Rusch, T. Mitsudomi, M. Tsuboi, E. Brambillae, W. D. Travis

Research output: Contribution to journalArticle

108 Citations (Scopus)

Abstract

A new adenocarcinoma classification was recently introduced by a joint working group of the International Association for the Study of Lung Cancer (IASLC), American Thoracic Society (ATS) and European Respiratory Society (ERS). A distinction is made between pre-invasive lesions, and minimally invasive and invasive adenocarcinoma. The confusing term "bronchioloalveolar carcinoma" is not used any more and new subcategories include adenocarcinoma in situ and minimally invasive adenocarcinoma. Due to a renewed interest in screen-detected nodules and early-stage lung cancers of <2 cm, this classification also has profound implications for thoracic surgeons. In this article, surgical topics are discussed: the role of a minimally invasive approach, especially video-assisted thoracic surgery, limited resection for early-stage lung cancer, the extent of lymph node dissection, the accuracy of intraoperative frozen section analysis, management of multiple lung nodules and prognostic factors in operated patients. Specific key issues are presented based on the current evidence and areas of surgical uncertainty are defined providing a basis for further studies. Thoracic surgeons will play a major role in the application and global introduction of this new adenocarcinoma classification. The remaining controversies regarding the precise diagnosis and management of early-stage lesions will have to be resolved by multidisciplinary and international collaboration. Copyright

Original languageEnglish
Pages (from-to)478-486
Number of pages9
JournalEuropean Respiratory Journal
Volume39
Issue number2
DOIs
Publication statusPublished - 2012 Feb 1
Externally publishedYes

Fingerprint

Lung Neoplasms
Adenocarcinoma
Thorax
Bronchiolo-Alveolar Adenocarcinoma
Video-Assisted Thoracic Surgery
Frozen Sections
Lymph Node Excision
Uncertainty
Joints
Lung
Surgeons

Keywords

  • Adenocarcinoma
  • Diagnosis
  • Lung cancer
  • Prognosis
  • Surgery
  • Video-assisted thoracic surgery

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Van Schil, P. E., Asamura, H., Rusch, V. W., Mitsudomi, T., Tsuboi, M., Brambillae, E., & Travis, W. D. (2012). Surgical implications of the new IASLC/ ATS/ERS adenocarcinoma classification. European Respiratory Journal, 39(2), 478-486. https://doi.org/10.1183/09031936.00027511

Surgical implications of the new IASLC/ ATS/ERS adenocarcinoma classification. / Van Schil, P. E.; Asamura, Hisao; Rusch, V. W.; Mitsudomi, T.; Tsuboi, M.; Brambillae, E.; Travis, W. D.

In: European Respiratory Journal, Vol. 39, No. 2, 01.02.2012, p. 478-486.

Research output: Contribution to journalArticle

Van Schil, PE, Asamura, H, Rusch, VW, Mitsudomi, T, Tsuboi, M, Brambillae, E & Travis, WD 2012, 'Surgical implications of the new IASLC/ ATS/ERS adenocarcinoma classification', European Respiratory Journal, vol. 39, no. 2, pp. 478-486. https://doi.org/10.1183/09031936.00027511
Van Schil, P. E. ; Asamura, Hisao ; Rusch, V. W. ; Mitsudomi, T. ; Tsuboi, M. ; Brambillae, E. ; Travis, W. D. / Surgical implications of the new IASLC/ ATS/ERS adenocarcinoma classification. In: European Respiratory Journal. 2012 ; Vol. 39, No. 2. pp. 478-486.
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