Surgical Resection of Remnant Gastric Cancer Following Distal Gastrectomy: A Retrospective Clinicopathological Study

Masashi Takahashi, Hiroya Takeuchi, Shinichi Tsuwano, Rieko Nakamura, Tsunehiro Takahashi, Norihito Wada, Hirofumi Kawakubo, Yoshiro Saikawa, Yuukou Kitagawa

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Abstract

Background: Remnant gastric cancer (RGC) is one of the less prevalent gastric cancers. The purpose of this study was to explore the clinicopathological characteristics and results of the operation of RGC following distal gastrectomy. In particular, we examined factors related to prognosis. Methods: Between January 1970 and December 2012, 122 patients with RGC following distal gastrectomy underwent further surgery and were analyzed retrospectively. Results: Initial gastric diseases included benign (49 patients, 40.2 %) and malignant diseases (73 patients, 59.8 %). Reconstructions by initial surgery included Billroth I (80 patients, 65.6 %) and Billroth II (42 patients, 34.4 %). Tumors were located at anastomotic (44 patients, 36.1 %) and nonanastomotic sites (78 patients, 63.9 %). There were 59 patients (48.4 %) classified with pathological (p) stage I, 19 as p stage II (15.6 %), 22 as p stage III (18.0 %), and 22 (18.0 %) as p stage IV. A total of 100 patients (82.0 %) underwent curative resection, and 22 underwent noncurative resection. The number of cases of postoperative morbidity, 90-day mortality, and adjuvant chemotherapy were 23 (18.9 %), 3 (2.5 %), and 20 (16.4 %), respectively. Univariate and multivariate analyses were performed to identify the prognostic factors of RGC. Multivariate analysis revealed historical periods, pathological venous invasion, curative resection, and postoperative morbidity to be independent prognostic factors. Conclusions: The prognosis of patients with RGC can be improved by aggressively performing curative resection without causing complications.

Original languageEnglish
JournalAnnals of Surgical Oncology
DOIs
Publication statusAccepted/In press - 2015 Jun 24

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Gastric Stump
Gastrectomy
Stomach Neoplasms
Retrospective Studies
Gastroenterostomy
Multivariate Analysis
Morbidity
Stomach Diseases
Adjuvant Chemotherapy

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

Surgical Resection of Remnant Gastric Cancer Following Distal Gastrectomy : A Retrospective Clinicopathological Study. / Takahashi, Masashi; Takeuchi, Hiroya; Tsuwano, Shinichi; Nakamura, Rieko; Takahashi, Tsunehiro; Wada, Norihito; Kawakubo, Hirofumi; Saikawa, Yoshiro; Kitagawa, Yuukou.

In: Annals of Surgical Oncology, 24.06.2015.

Research output: Contribution to journalArticle

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T2 - A Retrospective Clinicopathological Study

AU - Takahashi, Masashi

AU - Takeuchi, Hiroya

AU - Tsuwano, Shinichi

AU - Nakamura, Rieko

AU - Takahashi, Tsunehiro

AU - Wada, Norihito

AU - Kawakubo, Hirofumi

AU - Saikawa, Yoshiro

AU - Kitagawa, Yuukou

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