Surgical results and related factors for ossification of posterior longitudinal ligament of the thoracic spine

A multi-institutional retrospective study

Morio Matsumoto, Kazuhiro Chiba, Yoshiaki Toyama, Katsushi Takeshita, Atsushi Seichi, Kozo Nakamura, Jun Arimizu, Shunsuke Fujibayashi, Shigeru Hirabayashi, Toru Hirano, Motoki Iwasaki, Kouji Kaneoka, Yoshiharu Kawaguchi, Kosei Ijiri, Takeshi Maeda, Yukihiro Matsuyama, Yasuo Mikami, Hideki Murakami, Hideki Nagashima, Kensei Nagata & 18 others Shinnosuke Nakahara, Yutaka Nohara, Shiro Oka, Keizo Sakamoto, Yasuo Saruhashi, Yutaka Sasao, Katsuji Shimizu, Toshihiko Taguchi, Makoto Takahashi, Yasuhisa Tanaka, Toshikazu Tani, Yasuaki Tokuhashi, Kenzo Uchida, Kengo Yamamoto, Masashi Yamazaki, Toru Yokoyama, Munehito Yoshida, Yuji Nishiwaki

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

STUDY DESIGN. Retrospective multi-institutional study OBJECTIVE. To describe the surgical outcomes in patients with ossification of the posterior longitudinal ligament in the thoracic spine (T-OPLL) and to clarify factors related to the surgical outcomes. SUMMARY OF BACKGROUND DATA. Detailed analyses of surgical outcomes of T-OPLL have been difficult because of the rarity of this disease. METHODS. The subjects were 154 patients with T-OPLL who were surgically treated at 34 institutions between 1998 and 2002. The surgical procedures were laminectomy in 36, laminoplasty in 51, anterior decompression via anterior approach in 25 and via posterior approach in 29, combined anterior and posterior fusion in 8, and sternum splitting approach in 5 patients. Instrumentation was conducted in 52 patients. Assessments were made on (1) The Japanese Orthopedic Association (JOA) scores (full score, 11 points), its recovery rates, (2) factors related to surgical results, and (3) complications and their consequences. RESULTS. (1) The mean JOA score before surgery was 4.6 ± 2.0 and, 7.1 ± 2.5 after surgery. The mean recovery rate was 36.8% ± 47.4%. (2) The recovery rate was 50% or higher in 72 patients (46.8%). Factors significantly related to this were location of the maximum ossification (T1-T4) (odds ratio, 2.43-4.17) and the use of instrumentation (odds ratio, 3.37). (3) The frequent complications were deterioration of myelopathy immediately after surgery in 18 (11.7%) and dural injury in 34 (22.1%) patients. CONCLUSION. The factors significantly associated with favorable surgical results were maximum ossification located at the upper thoracic spine and use of instrumentation. T-OPLL at the nonkyphotic upper thoracic spine can be treated by laminoplasty that is relatively a safe surgical procedure for neural elements. The use of instrumentation allows correction of kyphosis or prevention of progression of kyphosis, thereby, enhancing and maintaining decompression effect, and its use should be considered with posterior decompression.

Original languageEnglish
Pages (from-to)1034-1041
Number of pages8
JournalSpine
Volume33
Issue number9
DOIs
Publication statusPublished - 2008 Apr

Fingerprint

Thorax
Retrospective Studies
Decompression
Kyphosis
Spine
Osteogenesis
Orthopedics
Odds Ratio
Ossification of Posterior Longitudinal Ligament
Sternum
Laminectomy
Spinal Cord Diseases
Ossification of the posterior longitudinal ligament of the spine
Wounds and Injuries
Laminoplasty

Keywords

  • Ossification of posterior longitudinal ligament
  • Spinal instrumentation
  • Surgical outcome
  • Thoracic spine

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Orthopedics and Sports Medicine

Cite this

Surgical results and related factors for ossification of posterior longitudinal ligament of the thoracic spine : A multi-institutional retrospective study. / Matsumoto, Morio; Chiba, Kazuhiro; Toyama, Yoshiaki; Takeshita, Katsushi; Seichi, Atsushi; Nakamura, Kozo; Arimizu, Jun; Fujibayashi, Shunsuke; Hirabayashi, Shigeru; Hirano, Toru; Iwasaki, Motoki; Kaneoka, Kouji; Kawaguchi, Yoshiharu; Ijiri, Kosei; Maeda, Takeshi; Matsuyama, Yukihiro; Mikami, Yasuo; Murakami, Hideki; Nagashima, Hideki; Nagata, Kensei; Nakahara, Shinnosuke; Nohara, Yutaka; Oka, Shiro; Sakamoto, Keizo; Saruhashi, Yasuo; Sasao, Yutaka; Shimizu, Katsuji; Taguchi, Toshihiko; Takahashi, Makoto; Tanaka, Yasuhisa; Tani, Toshikazu; Tokuhashi, Yasuaki; Uchida, Kenzo; Yamamoto, Kengo; Yamazaki, Masashi; Yokoyama, Toru; Yoshida, Munehito; Nishiwaki, Yuji.

In: Spine, Vol. 33, No. 9, 04.2008, p. 1034-1041.

Research output: Contribution to journalArticle

Matsumoto, M, Chiba, K, Toyama, Y, Takeshita, K, Seichi, A, Nakamura, K, Arimizu, J, Fujibayashi, S, Hirabayashi, S, Hirano, T, Iwasaki, M, Kaneoka, K, Kawaguchi, Y, Ijiri, K, Maeda, T, Matsuyama, Y, Mikami, Y, Murakami, H, Nagashima, H, Nagata, K, Nakahara, S, Nohara, Y, Oka, S, Sakamoto, K, Saruhashi, Y, Sasao, Y, Shimizu, K, Taguchi, T, Takahashi, M, Tanaka, Y, Tani, T, Tokuhashi, Y, Uchida, K, Yamamoto, K, Yamazaki, M, Yokoyama, T, Yoshida, M & Nishiwaki, Y 2008, 'Surgical results and related factors for ossification of posterior longitudinal ligament of the thoracic spine: A multi-institutional retrospective study', Spine, vol. 33, no. 9, pp. 1034-1041. https://doi.org/10.1097/BRS.0b013e31816c913b
Matsumoto, Morio ; Chiba, Kazuhiro ; Toyama, Yoshiaki ; Takeshita, Katsushi ; Seichi, Atsushi ; Nakamura, Kozo ; Arimizu, Jun ; Fujibayashi, Shunsuke ; Hirabayashi, Shigeru ; Hirano, Toru ; Iwasaki, Motoki ; Kaneoka, Kouji ; Kawaguchi, Yoshiharu ; Ijiri, Kosei ; Maeda, Takeshi ; Matsuyama, Yukihiro ; Mikami, Yasuo ; Murakami, Hideki ; Nagashima, Hideki ; Nagata, Kensei ; Nakahara, Shinnosuke ; Nohara, Yutaka ; Oka, Shiro ; Sakamoto, Keizo ; Saruhashi, Yasuo ; Sasao, Yutaka ; Shimizu, Katsuji ; Taguchi, Toshihiko ; Takahashi, Makoto ; Tanaka, Yasuhisa ; Tani, Toshikazu ; Tokuhashi, Yasuaki ; Uchida, Kenzo ; Yamamoto, Kengo ; Yamazaki, Masashi ; Yokoyama, Toru ; Yoshida, Munehito ; Nishiwaki, Yuji. / Surgical results and related factors for ossification of posterior longitudinal ligament of the thoracic spine : A multi-institutional retrospective study. In: Spine. 2008 ; Vol. 33, No. 9. pp. 1034-1041.
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TY - JOUR

T1 - Surgical results and related factors for ossification of posterior longitudinal ligament of the thoracic spine

T2 - A multi-institutional retrospective study

AU - Matsumoto, Morio

AU - Chiba, Kazuhiro

AU - Toyama, Yoshiaki

AU - Takeshita, Katsushi

AU - Seichi, Atsushi

AU - Nakamura, Kozo

AU - Arimizu, Jun

AU - Fujibayashi, Shunsuke

AU - Hirabayashi, Shigeru

AU - Hirano, Toru

AU - Iwasaki, Motoki

AU - Kaneoka, Kouji

AU - Kawaguchi, Yoshiharu

AU - Ijiri, Kosei

AU - Maeda, Takeshi

AU - Matsuyama, Yukihiro

AU - Mikami, Yasuo

AU - Murakami, Hideki

AU - Nagashima, Hideki

AU - Nagata, Kensei

AU - Nakahara, Shinnosuke

AU - Nohara, Yutaka

AU - Oka, Shiro

AU - Sakamoto, Keizo

AU - Saruhashi, Yasuo

AU - Sasao, Yutaka

AU - Shimizu, Katsuji

AU - Taguchi, Toshihiko

AU - Takahashi, Makoto

AU - Tanaka, Yasuhisa

AU - Tani, Toshikazu

AU - Tokuhashi, Yasuaki

AU - Uchida, Kenzo

AU - Yamamoto, Kengo

AU - Yamazaki, Masashi

AU - Yokoyama, Toru

AU - Yoshida, Munehito

AU - Nishiwaki, Yuji

PY - 2008/4

Y1 - 2008/4

N2 - STUDY DESIGN. Retrospective multi-institutional study OBJECTIVE. To describe the surgical outcomes in patients with ossification of the posterior longitudinal ligament in the thoracic spine (T-OPLL) and to clarify factors related to the surgical outcomes. SUMMARY OF BACKGROUND DATA. Detailed analyses of surgical outcomes of T-OPLL have been difficult because of the rarity of this disease. METHODS. The subjects were 154 patients with T-OPLL who were surgically treated at 34 institutions between 1998 and 2002. The surgical procedures were laminectomy in 36, laminoplasty in 51, anterior decompression via anterior approach in 25 and via posterior approach in 29, combined anterior and posterior fusion in 8, and sternum splitting approach in 5 patients. Instrumentation was conducted in 52 patients. Assessments were made on (1) The Japanese Orthopedic Association (JOA) scores (full score, 11 points), its recovery rates, (2) factors related to surgical results, and (3) complications and their consequences. RESULTS. (1) The mean JOA score before surgery was 4.6 ± 2.0 and, 7.1 ± 2.5 after surgery. The mean recovery rate was 36.8% ± 47.4%. (2) The recovery rate was 50% or higher in 72 patients (46.8%). Factors significantly related to this were location of the maximum ossification (T1-T4) (odds ratio, 2.43-4.17) and the use of instrumentation (odds ratio, 3.37). (3) The frequent complications were deterioration of myelopathy immediately after surgery in 18 (11.7%) and dural injury in 34 (22.1%) patients. CONCLUSION. The factors significantly associated with favorable surgical results were maximum ossification located at the upper thoracic spine and use of instrumentation. T-OPLL at the nonkyphotic upper thoracic spine can be treated by laminoplasty that is relatively a safe surgical procedure for neural elements. The use of instrumentation allows correction of kyphosis or prevention of progression of kyphosis, thereby, enhancing and maintaining decompression effect, and its use should be considered with posterior decompression.

AB - STUDY DESIGN. Retrospective multi-institutional study OBJECTIVE. To describe the surgical outcomes in patients with ossification of the posterior longitudinal ligament in the thoracic spine (T-OPLL) and to clarify factors related to the surgical outcomes. SUMMARY OF BACKGROUND DATA. Detailed analyses of surgical outcomes of T-OPLL have been difficult because of the rarity of this disease. METHODS. The subjects were 154 patients with T-OPLL who were surgically treated at 34 institutions between 1998 and 2002. The surgical procedures were laminectomy in 36, laminoplasty in 51, anterior decompression via anterior approach in 25 and via posterior approach in 29, combined anterior and posterior fusion in 8, and sternum splitting approach in 5 patients. Instrumentation was conducted in 52 patients. Assessments were made on (1) The Japanese Orthopedic Association (JOA) scores (full score, 11 points), its recovery rates, (2) factors related to surgical results, and (3) complications and their consequences. RESULTS. (1) The mean JOA score before surgery was 4.6 ± 2.0 and, 7.1 ± 2.5 after surgery. The mean recovery rate was 36.8% ± 47.4%. (2) The recovery rate was 50% or higher in 72 patients (46.8%). Factors significantly related to this were location of the maximum ossification (T1-T4) (odds ratio, 2.43-4.17) and the use of instrumentation (odds ratio, 3.37). (3) The frequent complications were deterioration of myelopathy immediately after surgery in 18 (11.7%) and dural injury in 34 (22.1%) patients. CONCLUSION. The factors significantly associated with favorable surgical results were maximum ossification located at the upper thoracic spine and use of instrumentation. T-OPLL at the nonkyphotic upper thoracic spine can be treated by laminoplasty that is relatively a safe surgical procedure for neural elements. The use of instrumentation allows correction of kyphosis or prevention of progression of kyphosis, thereby, enhancing and maintaining decompression effect, and its use should be considered with posterior decompression.

KW - Ossification of posterior longitudinal ligament

KW - Spinal instrumentation

KW - Surgical outcome

KW - Thoracic spine

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