Abstract
Background and Aim : The risk of developing colorectal cancer is higher in patients with ulcerative colitis (UC) than in the general population. Guidelines recommend surveillance colonoscopy (SCS) to reduce mortality ; however, few studies have assessed physicians' adherence to guidelines. This study was aimed to clarify the current status of SCS and adherence to guidelines through the characteristics of cancer/dysplasia surveillance for UC patients in Japan. Methods : A questionnaire was mailed to 541 physicians who attended meetings on inflammatory bowel disease. Results : The respondents encountered a median of 100 UC cases. Thirty percent of the respondents had never managed a UC patient with cancer. Fifty-one percent of the respondents had never diagnosed colorectal cancer with UC. Forty-seven percent of the respondents considered extensive colitis and left-sided colitis as indications for SCS, and 38% carried out SCS regardless of the disease extent. Sixty-three percent of the respondents started SCS at 7-10 years after UC onset, whereas 20% started SCS at 3 years or less. Fifty-two percent of the respondents obtained targeted biopsies only, and chromoendoscopy was used by 49% of the respondents as a special technique for surveillance. Median number of biopsies at SCS was five per patient ; it was three among patients whose biopsy was carried out by physicians who obtained targeted biopsies only and seven among those carried out by physicians who obtained step biopsies and targeted biopsies (P < 0.0001). Conclusion : A considerable proportion of the respondents did not follow the guidelines when selecting patients for surveillance and carrying out SCS.
| Original language | English |
|---|---|
| Pages (from-to) | 1033-1043 |
| Number of pages | 11 |
| Journal | Gastroenterological Endoscopy |
| Volume | 60 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2018 Apr 1 |
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ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Gastroenterology
Cite this
Surveillance for dysplasia in patients with ulcerative colitis : Discrepancy between guidelines and practice. / Shinozaki, Masaru; Kobayashi, Kiyonori; Kunisaki, Reiko; Hisamatsu, Tadakazu; Naganuma, Makoto; Takahashi, Ken Ichi; Iwao, Yasushi; Suzuki, Yasuo; Watanabe, Mamoru; Itabashi, Michio; Torii, Akira; Takazoe, Masakazu; Sugita, Akira.
In: Gastroenterological Endoscopy, Vol. 60, No. 4, 01.04.2018, p. 1033-1043.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Surveillance for dysplasia in patients with ulcerative colitis
T2 - Discrepancy between guidelines and practice
AU - Shinozaki, Masaru
AU - Kobayashi, Kiyonori
AU - Kunisaki, Reiko
AU - Hisamatsu, Tadakazu
AU - Naganuma, Makoto
AU - Takahashi, Ken Ichi
AU - Iwao, Yasushi
AU - Suzuki, Yasuo
AU - Watanabe, Mamoru
AU - Itabashi, Michio
AU - Torii, Akira
AU - Takazoe, Masakazu
AU - Sugita, Akira
PY - 2018/4/1
Y1 - 2018/4/1
N2 - Background and Aim : The risk of developing colorectal cancer is higher in patients with ulcerative colitis (UC) than in the general population. Guidelines recommend surveillance colonoscopy (SCS) to reduce mortality ; however, few studies have assessed physicians' adherence to guidelines. This study was aimed to clarify the current status of SCS and adherence to guidelines through the characteristics of cancer/dysplasia surveillance for UC patients in Japan. Methods : A questionnaire was mailed to 541 physicians who attended meetings on inflammatory bowel disease. Results : The respondents encountered a median of 100 UC cases. Thirty percent of the respondents had never managed a UC patient with cancer. Fifty-one percent of the respondents had never diagnosed colorectal cancer with UC. Forty-seven percent of the respondents considered extensive colitis and left-sided colitis as indications for SCS, and 38% carried out SCS regardless of the disease extent. Sixty-three percent of the respondents started SCS at 7-10 years after UC onset, whereas 20% started SCS at 3 years or less. Fifty-two percent of the respondents obtained targeted biopsies only, and chromoendoscopy was used by 49% of the respondents as a special technique for surveillance. Median number of biopsies at SCS was five per patient ; it was three among patients whose biopsy was carried out by physicians who obtained targeted biopsies only and seven among those carried out by physicians who obtained step biopsies and targeted biopsies (P < 0.0001). Conclusion : A considerable proportion of the respondents did not follow the guidelines when selecting patients for surveillance and carrying out SCS.
AB - Background and Aim : The risk of developing colorectal cancer is higher in patients with ulcerative colitis (UC) than in the general population. Guidelines recommend surveillance colonoscopy (SCS) to reduce mortality ; however, few studies have assessed physicians' adherence to guidelines. This study was aimed to clarify the current status of SCS and adherence to guidelines through the characteristics of cancer/dysplasia surveillance for UC patients in Japan. Methods : A questionnaire was mailed to 541 physicians who attended meetings on inflammatory bowel disease. Results : The respondents encountered a median of 100 UC cases. Thirty percent of the respondents had never managed a UC patient with cancer. Fifty-one percent of the respondents had never diagnosed colorectal cancer with UC. Forty-seven percent of the respondents considered extensive colitis and left-sided colitis as indications for SCS, and 38% carried out SCS regardless of the disease extent. Sixty-three percent of the respondents started SCS at 7-10 years after UC onset, whereas 20% started SCS at 3 years or less. Fifty-two percent of the respondents obtained targeted biopsies only, and chromoendoscopy was used by 49% of the respondents as a special technique for surveillance. Median number of biopsies at SCS was five per patient ; it was three among patients whose biopsy was carried out by physicians who obtained targeted biopsies only and seven among those carried out by physicians who obtained step biopsies and targeted biopsies (P < 0.0001). Conclusion : A considerable proportion of the respondents did not follow the guidelines when selecting patients for surveillance and carrying out SCS.
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U2 - 10.11280/gee.60.1033
DO - 10.11280/gee.60.1033
M3 - Article
AN - SCOPUS:85046132371
VL - 60
SP - 1033
EP - 1043
JO - Gastroenterological Endoscopy
JF - Gastroenterological Endoscopy
SN - 0387-1207
IS - 4
ER -