Symbiospirols: Novel long carbon-chain compounds isolated from symbiotic marine dinoflagellate Symbiodinium sp.

Yuta Tsunematsu, Osamu Ohno, Kaori Konishi, Kaoru Yamada, Masami Suganuma, Daisuke Uemura

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

Symbiospirols A, B, and C, long carbon-chain compounds with a molecular weight of 1207 were isolated from the cultured symbiotic dinoflagellate Symbiodinium sp. Their planar structures and partial relative stereochemistries were elucidated based on 1D and 2D NMR spectra and a degradation reaction. Symbiospirols consisted of a C67-linear chain with a β,β′- dihydroxyl ketone moiety, eight hydroxyl groups, one tetrahydropyran ring, and two 1,6-dioxaspiro[4,4]nonane rings. Symbiospirol A had an inhibitory effect against L-phosphatidylserine-induced PKC activation.

Original languageEnglish
Pages (from-to)2153-2156
Number of pages4
JournalOrganic Letters
Volume11
Issue number10
DOIs
Publication statusPublished - 2009 May 21

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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