Synchronization control for circadian rhythm of drosophila with flatness-based adaptive control

Tetsuya Kusumi, Hiromitsu Ohmori

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Recently, developing molecular biology and system biology, the mechanism of the circadian rhythm in which the inside of the body rhythm of the living thing is ruled is being clarified at the cell level. On the other hand, it is said that various sicknesses are related in the medicine and pharmacology to the disorder of the circadian rhythm. Therefore, it is thought that to restore an altered rhythm is a goal of these therapies. In this paper, we study the 10-states circadian model of Drosophila and propose a close-loop control based on flatness-based adaptive control to achieve circadian rhythm restoration.

Original languageEnglish
Title of host publicationProceedings of the SICE Annual Conference
Number of pages5
Publication statusPublished - 2007
EventSICE(Society of Instrument and Control Engineers)Annual Conference, SICE 2007 - Takamatsu, Japan
Duration: 2007 Sep 172007 Sep 20


OtherSICE(Society of Instrument and Control Engineers)Annual Conference, SICE 2007



  • Adaptive control
  • Circadian rhythm
  • Flatness-based control
  • Synchronization control
  • System biology

ASJC Scopus subject areas

  • Engineering(all)

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