Syntheses of model compounds related to an antigenic epitope in pectic polysaccharides from Bupleurum falcatum L. (II)

Yuhua Jin; Noriyasu Hada; Junko Oka; Osamu Kanie; Shusaku Daikoku; Yoshimi Kanie; Haruki Yamada; Tadahiro Takeda

doi:10.1248/cpb.54.485

Syntheses of model compounds related to an antigenic epitope in pectic polysaccharides from Bupleurum falcatum L. (II)

Yuhua Jin, Noriyasu Hada, Junko Oka, Osamu Kanie, Shusaku Daikoku, Yoshimi Kanie, Haruki Yamada, Tadahiro Takeda

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Stereocontrolled syntheses of model compounds related to a major antigenic epitope against antibupleurum 2IIc/PG-1-IgG from antiulcer pectic polysaccharide are described. A trisaccharide derivative (13) was prepared as a precursor and a novel and simple approach for the rational design of a glycocluster and glycodendrimer was developed, through the syntheses of the fluorescence-labeled glycocluster (2) and glycodendrimer (3).

Original language	English
Pages (from-to)	485-492
Number of pages	8
Journal	Chemical and Pharmaceutical Bulletin
Volume	54
Issue number	4
DOIs	https://doi.org/10.1248/cpb.54.485
Publication status	Published - 2006 Apr
Externally published	Yes

Keywords

B-alanine derivative
Bupleurum falcatum
Chemical synthesis
Glycocluster
Glycodendrimer

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

Access to Document

10.1248/cpb.54.485

Cite this

@article{b040b0598ca14d9bbfd07b63a40e3634,

title = "Syntheses of model compounds related to an antigenic epitope in pectic polysaccharides from Bupleurum falcatum L. (II)",

abstract = "Stereocontrolled syntheses of model compounds related to a major antigenic epitope against antibupleurum 2IIc/PG-1-IgG from antiulcer pectic polysaccharide are described. A trisaccharide derivative (13) was prepared as a precursor and a novel and simple approach for the rational design of a glycocluster and glycodendrimer was developed, through the syntheses of the fluorescence-labeled glycocluster (2) and glycodendrimer (3).",

keywords = "B-alanine derivative, Bupleurum falcatum, Chemical synthesis, Glycocluster, Glycodendrimer",

author = "Yuhua Jin and Noriyasu Hada and Junko Oka and Osamu Kanie and Shusaku Daikoku and Yoshimi Kanie and Haruki Yamada and Tadahiro Takeda",

year = "2006",

month = apr,

doi = "10.1248/cpb.54.485",

language = "English",

volume = "54",

pages = "485--492",

journal = "Chemical and Pharmaceutical Bulletin",

issn = "0009-2363",

publisher = "Pharmaceutical Society of Japan",

number = "4",

}

TY - JOUR

T1 - Syntheses of model compounds related to an antigenic epitope in pectic polysaccharides from Bupleurum falcatum L. (II)

AU - Jin, Yuhua

AU - Hada, Noriyasu

AU - Oka, Junko

AU - Kanie, Osamu

AU - Daikoku, Shusaku

AU - Kanie, Yoshimi

AU - Yamada, Haruki

AU - Takeda, Tadahiro

PY - 2006/4

Y1 - 2006/4

N2 - Stereocontrolled syntheses of model compounds related to a major antigenic epitope against antibupleurum 2IIc/PG-1-IgG from antiulcer pectic polysaccharide are described. A trisaccharide derivative (13) was prepared as a precursor and a novel and simple approach for the rational design of a glycocluster and glycodendrimer was developed, through the syntheses of the fluorescence-labeled glycocluster (2) and glycodendrimer (3).

AB - Stereocontrolled syntheses of model compounds related to a major antigenic epitope against antibupleurum 2IIc/PG-1-IgG from antiulcer pectic polysaccharide are described. A trisaccharide derivative (13) was prepared as a precursor and a novel and simple approach for the rational design of a glycocluster and glycodendrimer was developed, through the syntheses of the fluorescence-labeled glycocluster (2) and glycodendrimer (3).

KW - B-alanine derivative

KW - Bupleurum falcatum

KW - Chemical synthesis

KW - Glycocluster

KW - Glycodendrimer

UR - http://www.scopus.com/inward/record.url?scp=33645545304&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645545304&partnerID=8YFLogxK

U2 - 10.1248/cpb.54.485

DO - 10.1248/cpb.54.485

M3 - Article

C2 - 16595950

AN - SCOPUS:33645545304

SN - 0009-2363

VL - 54

SP - 485

EP - 492

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 4

ER -

Syntheses of model compounds related to an antigenic epitope in pectic polysaccharides from Bupleurum falcatum L. (II)

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this