Synthesis and cytotoxicity of aurilide analogs

Kiyotake Suenaga; Shuri Kajiwara; Satomi Kuribayashi; Tomohisa Handa; Hideo Kigoshi

doi:10.1016/j.bmcl.2008.06.035

Synthesis and cytotoxicity of aurilide analogs

Kiyotake Suenaga, Shuri Kajiwara, Satomi Kuribayashi, Tomohisa Handa, Hideo Kigoshi

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure-activity relationships were investigated.

Original language	English
Pages (from-to)	3902-3905
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	18
Issue number	14
DOIs	https://doi.org/10.1016/j.bmcl.2008.06.035
Publication status	Published - 2008 Jul 15

Keywords

Aurilide
Cyclodepsipeptide
Cytotoxicity
Structure-activity relationships

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.bmcl.2008.06.035

Cite this

@article{cd4ac265428145df8585a3e13265762c,

title = "Synthesis and cytotoxicity of aurilide analogs",

abstract = "The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure-activity relationships were investigated.",

keywords = "Aurilide, Cyclodepsipeptide, Cytotoxicity, Structure-activity relationships",

author = "Kiyotake Suenaga and Shuri Kajiwara and Satomi Kuribayashi and Tomohisa Handa and Hideo Kigoshi",

note = "Funding Information: This work was supported in part by Grants-in-Aid for Scientific Research on Priority Areas (No. 06240103) and COE Research (No. 07CE2004), and Grants-in-Aid for Young Scientists (No. 15710166) from the Ministry of Education, Culture, Sports, Science and Technology, Japan, the Uehara Memorial Foundation, and Keio Gijuku Academic Development Funds. ",

year = "2008",

month = jul,

day = "15",

doi = "10.1016/j.bmcl.2008.06.035",

language = "English",

volume = "18",

pages = "3902--3905",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier Limited",

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}

TY - JOUR

T1 - Synthesis and cytotoxicity of aurilide analogs

AU - Suenaga, Kiyotake

AU - Kajiwara, Shuri

AU - Kuribayashi, Satomi

AU - Handa, Tomohisa

AU - Kigoshi, Hideo

N1 - Funding Information: This work was supported in part by Grants-in-Aid for Scientific Research on Priority Areas (No. 06240103) and COE Research (No. 07CE2004), and Grants-in-Aid for Young Scientists (No. 15710166) from the Ministry of Education, Culture, Sports, Science and Technology, Japan, the Uehara Memorial Foundation, and Keio Gijuku Academic Development Funds.

PY - 2008/7/15

Y1 - 2008/7/15

N2 - The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure-activity relationships were investigated.

AB - The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure-activity relationships were investigated.

KW - Aurilide

KW - Cyclodepsipeptide

KW - Cytotoxicity

KW - Structure-activity relationships

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U2 - 10.1016/j.bmcl.2008.06.035

DO - 10.1016/j.bmcl.2008.06.035

M3 - Article

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AN - SCOPUS:47249089015

VL - 18

SP - 3902

EP - 3905

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

SN - 0960-894X

IS - 14

ER -

Synthesis and cytotoxicity of aurilide analogs

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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