Synthesis and cytotoxicity of aurilide analogs

Kiyotake Suenaga; Shuri Kajiwara; Satomi Kuribayashi; Tomohisa Handa; Hideo Kigoshi

doi:10.1016/j.bmcl.2008.06.035

Synthesis and cytotoxicity of aurilide analogs

Kiyotake Suenaga, Shuri Kajiwara, Satomi Kuribayashi, Tomohisa Handa, Hideo Kigoshi

Department of Chemistry

Research output: Contribution to journal › Article

25 Citations (Scopus)

Abstract

The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure-activity relationships were investigated.

Original language	English
Pages (from-to)	3902-3905
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	18
Issue number	14
DOIs	https://doi.org/10.1016/j.bmcl.2008.06.035
Publication status	Published - 2008 Jul 15

Keywords

Aurilide
Cyclodepsipeptide
Cytotoxicity
Structure-activity relationships

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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10.1016/j.bmcl.2008.06.035

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Suenaga, K., Kajiwara, S., Kuribayashi, S., Handa, T., & Kigoshi, H. (2008). Synthesis and cytotoxicity of aurilide analogs. Bioorganic and Medicinal Chemistry Letters, 18(14), 3902-3905. https://doi.org/10.1016/j.bmcl.2008.06.035

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abstract = "The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure-activity relationships were investigated.",

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AU - Kigoshi, Hideo

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