Synthesis and cytotoxicity of aurilide analogs

Kiyotake Suenaga; Shuri Kajiwara; Satomi Kuribayashi; Tomohisa Handa; Hideo Kigoshi

doi:10.1016/j.bmcl.2008.06.035

Synthesis and cytotoxicity of aurilide analogs

Kiyotake Suenaga, Shuri Kajiwara, Satomi Kuribayashi, Tomohisa Handa, Hideo Kigoshi

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure-activity relationships were investigated.

Original language	English
Pages (from-to)	3902-3905
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	18
Issue number	14
DOIs	https://doi.org/10.1016/j.bmcl.2008.06.035
Publication status	Published - 2008 Jul 15

Keywords

Aurilide
Cyclodepsipeptide
Cytotoxicity
Structure-activity relationships

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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title = "Synthesis and cytotoxicity of aurilide analogs",

abstract = "The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure-activity relationships were investigated.",

keywords = "Aurilide, Cyclodepsipeptide, Cytotoxicity, Structure-activity relationships",

author = "Kiyotake Suenaga and Shuri Kajiwara and Satomi Kuribayashi and Tomohisa Handa and Hideo Kigoshi",

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AU - Kajiwara, Shuri

AU - Kuribayashi, Satomi

AU - Handa, Tomohisa

AU - Kigoshi, Hideo

PY - 2008/7/15

Y1 - 2008/7/15

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KW - Cyclodepsipeptide

KW - Cytotoxicity

KW - Structure-activity relationships

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