Synthesis and cytotoxicity of aurilide analogs

Kiyotake Suenaga, Shuri Kajiwara, Satomi Kuribayashi, Tomohisa Handa, Hideo Kigoshi

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure-activity relationships were investigated.

Original languageEnglish
Pages (from-to)3902-3905
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume18
Issue number14
DOIs
Publication statusPublished - 2008 Jul 15

Keywords

  • Aurilide
  • Cyclodepsipeptide
  • Cytotoxicity
  • Structure-activity relationships

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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