Synthesis and cytotoxicity of aurilide analogs

Kiyotake Suenaga, Shuri Kajiwara, Satomi Kuribayashi, Tomohisa Handa, Hideo Kigoshi

Research output: Contribution to journal › Article

24 Citations (Scopus)

Abstract

The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure-activity relationships were investigated.

Original languageEnglish
Pages (from-to)3902-3905
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume18
Issue number14
DOIs
Publication statusPublished - 2008 Jul 15

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Depsipeptides
Structure-Activity Relationship
Cytotoxicity
aurilide

Keywords

  • Aurilide
  • Cyclodepsipeptide
  • Cytotoxicity
  • Structure-activity relationships

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science

Cite this

Synthesis and cytotoxicity of aurilide analogs. / Suenaga, Kiyotake; Kajiwara, Shuri; Kuribayashi, Satomi; Handa, Tomohisa; Kigoshi, Hideo.

In: Bioorganic and Medicinal Chemistry Letters, Vol. 18, No. 14, 15.07.2008, p. 3902-3905.

Research output: Contribution to journal › Article

Suenaga, K, Kajiwara, S, Kuribayashi, S, Handa, T & Kigoshi, H 2008, 'Synthesis and cytotoxicity of aurilide analogs', Bioorganic and Medicinal Chemistry Letters, vol. 18, no. 14, pp. 3902-3905. https://doi.org/10.1016/j.bmcl.2008.06.035
Suenaga K, Kajiwara S, Kuribayashi S, Handa T, Kigoshi H. Synthesis and cytotoxicity of aurilide analogs. Bioorganic and Medicinal Chemistry Letters. 2008 Jul 15;18(14):3902-3905. https://doi.org/10.1016/j.bmcl.2008.06.035
Suenaga, Kiyotake ; Kajiwara, Shuri ; Kuribayashi, Satomi ; Handa, Tomohisa ; Kigoshi, Hideo. / Synthesis and cytotoxicity of aurilide analogs. In: Bioorganic and Medicinal Chemistry Letters. 2008 ; Vol. 18, No. 14. pp. 3902-3905.
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