Synthesis of cationic water-soluble esters of chlorin e6

Hidetoshi Taima; Akihiro Okubo; Naoki Yoshioka; Hidenari Inoue

doi:10.1016/j.tetlet.2005.04.069

Synthesis of cationic water-soluble esters of chlorin e₆

Hidetoshi Taima, Akihiro Okubo, Naoki Yoshioka, Hidenari Inoue

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

Two esters of chlorin e₆ have been synthesized by esterification with aminoalcohols via the formation of acid chloride using oxalyl chloride and converted to the corresponding cationic water-soluble esters of chlorin e ₆. The visible absorption and circular dichroism spectra have revealed that these two cationic chlorin e₆ esters synthesized are readily soluble in water as a monomer.

Original language	English
Pages (from-to)	4161-4164
Number of pages	4
Journal	Tetrahedron Letters
Volume	46
Issue number	24
DOIs	https://doi.org/10.1016/j.tetlet.2005.04.069
Publication status	Published - 2005 Jun 13

Keywords

Cationic chlorin
Chlorin e
Chlorophyll
Esterification
Oxalyl chloride
Water-soluble chlorin

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/j.tetlet.2005.04.069

Cite this

@article{c3b9cc792da84efdb795529559625942,

title = "Synthesis of cationic water-soluble esters of chlorin e6",

abstract = "Two esters of chlorin e6 have been synthesized by esterification with aminoalcohols via the formation of acid chloride using oxalyl chloride and converted to the corresponding cationic water-soluble esters of chlorin e 6. The visible absorption and circular dichroism spectra have revealed that these two cationic chlorin e6 esters synthesized are readily soluble in water as a monomer.",

keywords = "Cationic chlorin, Chlorin e, Chlorophyll, Esterification, Oxalyl chloride, Water-soluble chlorin",

author = "Hidetoshi Taima and Akihiro Okubo and Naoki Yoshioka and Hidenari Inoue",

note = "Funding Information: This work was supported in part by a Grant-in-Aid for Scientific Research (No. 13554025) from the Ministry of Education, Culture, Sports, Science and Technology of the Japanese Government.",

year = "2005",

month = jun,

day = "13",

doi = "10.1016/j.tetlet.2005.04.069",

language = "English",

volume = "46",

pages = "4161--4164",

journal = "Tetrahedron Letters",

issn = "0040-4039",

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TY - JOUR

T1 - Synthesis of cationic water-soluble esters of chlorin e6

AU - Taima, Hidetoshi

AU - Okubo, Akihiro

AU - Yoshioka, Naoki

AU - Inoue, Hidenari

N1 - Funding Information: This work was supported in part by a Grant-in-Aid for Scientific Research (No. 13554025) from the Ministry of Education, Culture, Sports, Science and Technology of the Japanese Government.

PY - 2005/6/13

Y1 - 2005/6/13

N2 - Two esters of chlorin e6 have been synthesized by esterification with aminoalcohols via the formation of acid chloride using oxalyl chloride and converted to the corresponding cationic water-soluble esters of chlorin e 6. The visible absorption and circular dichroism spectra have revealed that these two cationic chlorin e6 esters synthesized are readily soluble in water as a monomer.

AB - Two esters of chlorin e6 have been synthesized by esterification with aminoalcohols via the formation of acid chloride using oxalyl chloride and converted to the corresponding cationic water-soluble esters of chlorin e 6. The visible absorption and circular dichroism spectra have revealed that these two cationic chlorin e6 esters synthesized are readily soluble in water as a monomer.

KW - Cationic chlorin

KW - Chlorin e

KW - Chlorophyll

KW - Esterification

KW - Oxalyl chloride

KW - Water-soluble chlorin

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U2 - 10.1016/j.tetlet.2005.04.069

DO - 10.1016/j.tetlet.2005.04.069

M3 - Article

AN - SCOPUS:19044387124

SN - 0040-4039

VL - 46

SP - 4161

EP - 4164

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 24

ER -